Conference: SMBE Satellite Meeting On De Novo Gene Birth

该会议奖提供部分支持的分子生物学和进化卫星会议的社会从头基因诞生，将在学院站，德克萨斯州11月6日至9日，2023年。从头基因诞生是最近发现的一种遗传过程，负责产生具有重要生物学作用的新基因，例如人类大脑功能和作物抗虫性。对从头基因的研究对于我们理解物种进化至关重要，并且对医学科学（包括癌症生物学）的影响越来越大。这次国际会议将刺激新知识的共享并促进各个生物学科的合作。会议将为代表未来STEM劳动力的年轻研究人员提供出色的网络和培训机会。 从头基因从祖先的非编码DNA序列进化而来，在生命之树中无处不在。这一领域的研究涵盖了一系列学科，并为生物科学中更广泛的现象提供了信息，包括细胞网络的进化，新蛋白质折叠和结构域的出现以及基因注释的准确性。基因组序列和高通量蛋白质组学数据集的快速增加为解决从头基因起源和功能的基本问题提供了丰富的信息。作为关于从头基因诞生的第一次大型科学聚会，本次会议将加速从头基因进化，功能和注释的进展，并能够开发概念和经验框架，以指导在可预见的未来这一领域的研究。会议将为早期职业研究人员提供机会，介绍他们的工作，并与分子进化，基因组学，蛋白质组学，细胞生物学和生物信息学方面的国际公认学者建立更广泛的专业网络。NSF提供的资金包括支持历史上代表性不足的科学团体的学员，目的是扩大对会议的参与。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This conference award provides partial support for The Society of Molecular Biology and Evolution Satellite Meeting on De Novo Gene Birth, to be held in College Station, TX on November 6-9, 2023. De novo gene birth is a recently discovered genetic process responsible for generating new genes with important biological roles, such as human brain function and pest resistance in crops. Research on de novo genes is critical to our understanding of species evolution and has a growing impact on medical sciences, including cancer biology. This international meeting will stimulate sharing of new knowledge and foster collaborative efforts across a variety of biological disciplines. The conference will offer outstanding networking and training opportunities for young researchers representing the future STEM workforce. De novo genes evolve from ancestrally noncoding DNA sequences and are ubiquitous across the tree of life. Research in this area encompasses a range of disciplines and has informed on broader phenomena in biological sciences, including the evolution of cellular networks, the emergence of new protein folds and domains, and the accuracy of gene annotation. The rapid increase of genome sequences and high-throughput proteomic datasets is providing the wealth of information necessary to address fundamental issues in de novo gene origin and function. As the first large scientific gathering on de novo gene birth, this conference will accelerate advances in de novo gene evolution, function, and annotation, and enable developing the conceptual and empirical frameworks that will guide investigations in this area for the foreseeable future. The meeting will provide opportunities for early-career researchers to present their work and establish a broader professional network with internationally recognized scholars in molecular evolution, genomics, proteomics, cell biology and bioinformatics. The funding provided by NSF includes support to trainees from historically underrepresented groups in science with the goal of broadening participation to the meeting.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.