Conference: SMBE Satellite Meeting On De Novo Gene Birth

这一会议奖为将于2023年11月6-9日在德克萨斯州大学站举行的德诺沃基因诞生卫星会议提供了部分支持。新基因诞生是新近发现的一种遗传过程，负责产生具有重要生物学作用的新基因，如人脑功能和作物抗虫性等。对从头基因的研究对我们理解物种进化至关重要，并对包括癌症生物学在内的医学科学产生越来越大的影响。这次国际会议将促进新知识的分享，并促进各种生物学学科的合作努力。会议将为代表未来STEM劳动力的年轻研究人员提供出色的网络和培训机会。从头基因从祖先的非编码DNA序列进化而来，在生命之树中无处不在。这一领域的研究涵盖了一系列学科，并为生物科学中更广泛的现象提供了信息，包括细胞网络的进化、新蛋白质折叠和结构域的出现以及基因注释的准确性。基因组序列和高通量蛋白质组数据集的快速增长为解决从头基因起源和功能的基本问题提供了丰富的信息。作为关于从头基因诞生的第一次大型科学会议，这次会议将加速从头基因的进化、功能和注释的进展，并使发展概念和经验框架能够在可预见的未来指导这一领域的研究。会议将为职业生涯早期的研究人员提供介绍他们的工作的机会，并与分子进化、基因组学、蛋白质组学、细胞生物学和生物信息学方面的国际公认的学者建立更广泛的专业网络。NSF提供的资金包括支持来自科学界历史上代表性不足的群体的受训人员，目标是扩大会议的参与度。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This conference award provides partial support for The Society of Molecular Biology and Evolution Satellite Meeting on De Novo Gene Birth, to be held in College Station, TX on November 6-9, 2023. De novo gene birth is a recently discovered genetic process responsible for generating new genes with important biological roles, such as human brain function and pest resistance in crops. Research on de novo genes is critical to our understanding of species evolution and has a growing impact on medical sciences, including cancer biology. This international meeting will stimulate sharing of new knowledge and foster collaborative efforts across a variety of biological disciplines. The conference will offer outstanding networking and training opportunities for young researchers representing the future STEM workforce. De novo genes evolve from ancestrally noncoding DNA sequences and are ubiquitous across the tree of life. Research in this area encompasses a range of disciplines and has informed on broader phenomena in biological sciences, including the evolution of cellular networks, the emergence of new protein folds and domains, and the accuracy of gene annotation. The rapid increase of genome sequences and high-throughput proteomic datasets is providing the wealth of information necessary to address fundamental issues in de novo gene origin and function. As the first large scientific gathering on de novo gene birth, this conference will accelerate advances in de novo gene evolution, function, and annotation, and enable developing the conceptual and empirical frameworks that will guide investigations in this area for the foreseeable future. The meeting will provide opportunities for early-career researchers to present their work and establish a broader professional network with internationally recognized scholars in molecular evolution, genomics, proteomics, cell biology and bioinformatics. The funding provided by NSF includes support to trainees from historically underrepresented groups in science with the goal of broadening participation to the meeting.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.