Biomechanical investigations on the meniscus under dynamic and shock loading conditions
动态和冲击载荷条件下半月板的生物力学研究
基本信息
- 批准号:255994026
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:德国
- 项目类别:Research Grants
- 财政年份:2014
- 资助国家:德国
- 起止时间:2013-12-31 至 2017-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Partial meniscal resection is still the most frequent surgical procedure performed on the meniscus. It results in an increased contact pressure leading to a higher risk of premature cartilage degeneration. To overcome this problem some attempts have been conducted to replace the meniscus. However, due to the insufficient mechanical properties of the used materials these approaches have not yet been successful. By now, it is not completely understood, which mechanical loads meniscal implants are exposed to. Biomechanical investigations revealed only low tensile loads acting in the meniscal attachments during quasistatic loading conditions and during slow knee flexion-extension movements. This contradicts to the high strength of these ligaments. It is therefore hypothesized that these forces are considerably higher during dynamic movements and shock loads, as they typically occur e.g. in sports. This might have strong implications for the requirements and the design of meniscal replacement implants. To investigate this, a new dynamic knee joint simulator should be developed, which enables the creation of almost physiological loading conditions, as they occur e.g. during jump landing or under axial or rotational shock loads. The simulator will be based on an Oxford-Rig design, in which the knee joint specimen is mounted. A vertically moving cross head driven by a hydraulic actuator dynamically moves the knee joint under consideration of all required degrees of freedom. To achieve realistic joint and ground reaction forces the most important knee spanning muscle groups are simulated. The magnitude of these muscles forces and their transient characteristics during dynamic activities are calculated using inverse dynamics by a subcontractor. After designing and manufacturing the simulator will be validated with an idealized knee joint model. Subsequently, in vitro experiments on 20 knee joint specimens will be carried out to determine the loads acting on the menisci and their attachments under dynamic and shock loads. During all experiments the strain occurring in the meniscal attachments and in the meniscal periphery and the tibiofemoral contact pressure are continuously registered. Finally, tensile tests on isolated meniscal attachments are carried out to deduce the forces from the strains, which were measured during the simulator experiments. Furthermore, the new knee joint simulator will enable for a variety of other experiments requiring dynamic or shock loading conditions on e.g. meniscus, ligaments or knee joint arthroplasty.
半月板部分切除仍然是半月板最常用的手术方法。它导致接触压力增加,导致软骨过早变性的风险更高。为了克服这个问题,已经进行了一些更换半月板的尝试。然而,由于所用材料的机械性能不足,这些方法尚未成功。到目前为止,还没有完全了解半月板植入物暴露在何种机械载荷下。生物力学研究显示,在准静态加载条件下和缓慢的膝关节屈伸运动中,只有低拉伸载荷作用于半月板附着体。这与这些韧带的高强度相矛盾。因此,假设这些力在动态运动和冲击载荷中相当高,因为它们通常发生在运动中。这可能对半月板置换植入物的要求和设计有很大的影响。为了研究这一点,应该开发一种新的动态膝关节模拟器,它可以创建几乎生理的负载条件,因为它们发生在跳跃着陆或轴向或旋转冲击载荷下。该模拟器将基于Oxford-Rig设计,其中膝关节标本安装在其中。在液压致动器的驱动下,垂直移动的十字头在考虑所有所需自由度的情况下动态移动膝关节。为了获得真实的关节和地面反作用力,模拟了最重要的跨膝肌群。这些肌肉力量的大小及其在动态活动中的瞬态特性由分包商使用逆动力学计算。在设计和制造完成后,将用理想的膝关节模型对仿真器进行验证。随后,将对20个膝关节标本进行体外实验,以确定在动态和冲击载荷下半月板及其附着体所受的载荷。在所有的实验中,发生在半月板附着物和半月板周围的应变和胫股接触压力被连续记录。最后,对孤立的半月板附件进行拉伸试验,从应变中推导出在模拟器实验中测量的力。此外,新的膝关节模拟器将支持各种其他需要动态或冲击载荷条件的实验,例如半月板,韧带或膝关节置换术。
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Dynamische Bewegungen vervielfachen die Belastungen im Meniskus und seinen Verankerungsligamenten
动态运动会增加半月板及其锚定韧带上的负载
- DOI:10.18725/oparu-15719
- 发表时间:2019
- 期刊:
- 影响因子:0
- 作者:Schall;Hacker;van Drongelen;Ignatius;Dürselen
- 通讯作者:Dürselen
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Professor Dr. Lutz Dürselen其他文献
Professor Dr. Lutz Dürselen的其他文献
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{{ truncateString('Professor Dr. Lutz Dürselen', 18)}}的其他基金
Biomechanik des Meniskus und seiner Verankerung
半月板及其锚定的生物力学
- 批准号:
50909352 - 财政年份:2008
- 资助金额:
-- - 项目类别:
Research Grants
Development, validation and application of a non-invasive dynamic method for the quantitative analysis of the altered shoulder kinematics in specific diseases
用于定量分析特定疾病中肩部运动学改变的非侵入性动态方法的开发、验证和应用
- 批准号:
5397258 - 财政年份:2003
- 资助金额:
-- - 项目类别:
Research Grants
Ersatz des vorderen Kreuzbandes mit Hilfe computerunterstützter Chirurgie
使用计算机辅助手术置换前十字韧带
- 批准号:
5369398 - 财政年份:1997
- 资助金额:
-- - 项目类别:
Research Grants
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