Collaborative Research: RUI: Life history strategies within a population depend on cellular and organismal traits that underlie differences in resource acquisition and allocation

合作研究：RUI：群体内的生活史策略取决于细胞和有机体特征，这些特征是资源获取和分配差异的基础

• 批准号: 2314381
• 负责人: Patricia Jones
• 金额: $ 40.67万
• 依托单位: Bowdoin College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-12-01 至 2026-11-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2314381&HistoricalAwards=false
• 关键词: Collaborative; Research; RUI; Life; history

All organisms need energy to fuel the biological processes of life. In general, this energy can be allocated to three broad categories: growth, self-maintenance, and reproduction. Said in another way, organisms can allocate acquired energy to grow their body to achieve a larger size, to repair and maintain their body to live longer, or to reproduce and create the new bodies of their offspring. However energy is limiting, so if more is invested into growth, less can be invested into self-maintenance and reproduction. This results in allocation trade-offs, where some individuals are better at growing, while others may be able to attain extreme longevity. While these patterns generally hold in animals, in many species scientist’s observe certain individuals who appear to be able to do it all with few consequences, but little is known about how this occurs. This proposal studies a long-lived seabird, Leach's storm-petrels, that has been studied continuously at our site for the past 70 years. This has revealed that while we have many individuals who show the expected allocation trade-offs there are also many that somehow have escaped that trade-off. Our work explores the molecular and cellular processes that underlie the ability to avoid this trade-off. This work is focused on a fundamental question in biology, and will help us to understand how molecular processes and organismal performance affect longevity. This work also strongly supports undergraduate science education, and will result in the development of inquiry-based scientific modules used in middle school and high school classrooms.Factors driving the evolution of diverse life history strategies both within and between species remain a fundamental question in ecology and evolutionary biology. Because resources are finite, many life history traits are subject to intrinsic trade-offs. However, theoretical models have proposed that variation in individual acquisition of resources can produce apparent positive correlations between investment in reproduction and investment in survival instead of the expected trade-off. This proposal tests these models by examining phenotypic variation in strategies to balance the trade-off between current reproduction and survival in a long-lived seabird, Leach's storm-petrels (Hydrobates leucorhous), that has been studied continuously at our site since 1953. This proposal has three primary objectives: 1) to better understand the molecular, cellular, and organismal performance traits that underlie the observed variation in trade-off strategies in this population, and 2) to determine if individuals who appear to escape the trade-off do so via higher foraging efficiency as proposed in theoretical models, and 3) to determine whether these trade-off strategies are fixed or plastic in response to environmental variability. The proposed research is informed by our 70-year demographic data set, and utilizes (i) a combination of novel technology and molecular tools to understand the molecular, cellular, and organismal performance traits that underlie the observed variation in trade-off strategies, and (ii) experimental manipulations to explore whether these strategies are fixed or plastic.This project is jointly funded by the Integrative Ecological Physiology Program and the Established Program to Stimulate Competitive Research (EPSCoR).This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

所有生物体都需要能量来维持生命的生物过程。一般来说，这种能量可以分为三大类：生长、自我维持和繁殖。换句话说，生物体可以分配获得的能量来生长他们的身体以获得更大的尺寸，修复和维护他们的身体以延长寿命，或者繁殖和创造他们后代的新身体。然而，能量是有限的，所以如果更多地投资于增长，那么可以投资于自我维持和繁殖的就少了。这导致了分配的权衡，其中一些个体更擅长生长，而另一些个体可能能够获得极长的寿命。虽然这些模式通常适用于动物，但在许多物种中，科学家观察到某些个体似乎能够做到这一切而几乎没有后果，但对这是如何发生的知之甚少。这项建议研究了一种长寿的海鸟，利奇的风暴海燕，这一直在我们的网站在过去的70年中不断研究。这表明，虽然我们有许多人表现出预期的分配权衡，但也有许多人不知何故逃脱了这种权衡。我们的工作探索了避免这种权衡的能力的分子和细胞过程。这项工作的重点是生物学中的一个基本问题，并将帮助我们了解分子过程和生物体性能如何影响寿命。这项工作也有力地支持本科科学教育，并将导致在初中和高中classicals.Factors驱动不同的生活史策略的进化内和物种之间的发展探究为基础的科学模块仍然是生态学和进化生物学的一个基本问题。因为资源是有限的，许多生活史特征都受到内在权衡的影响。然而，理论模型已经提出，个体获取资源的变化可以在再生产投资和生存投资之间产生明显的正相关关系，而不是预期的权衡。该提案测试这些模型，通过检查表型变化的策略，以平衡目前的繁殖和生存之间的权衡，在一个长寿的海鸟，利奇的风暴海燕（Hydrobates leucorhous），一直在我们的网站研究自1953年以来。该提案有三个主要目标：1）更好地理解在这个群体中观察到的权衡策略变化的基础上的分子，细胞和生物体性能特征，以及2）确定似乎逃避权衡的个体是否通过理论模型中提出的更高的觅食效率来这样做，以及3）确定这些权衡策略是固定的还是适应环境变化的可塑性的。拟议的研究是由我们70年的人口统计数据集，并利用（i）新技术和分子工具的组合，以了解分子，细胞和生物体的性能特征，这些特征是观察到的权衡策略变化的基础，和（ii）实验操作，以探索这些策略是固定的还是可塑的。该项目由综合生态生理学计划共同资助该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。