Postdoctoral Fellowship: MPS-Ascend: Development of Selective Reaction Schemes for Photoactivation of Alcohols

Robert T.马丁被授予NSF数学和物理科学上升博士后研究奖学金（NSF MPS-Ascend），以开展与扩大STEM中代表性不足的群体参与有关的研究和活动计划。Martin博士的奖学金支持在赞助科学家的指导下进行的题为“MPS-Ascend：开发用于酒精光活化的选择性反应方案”的研究项目。该奖学金的主办机构是普林斯顿大学，赞助科学家是大卫W博士。C.该提案旨在开发有机合成方法，以扩大使用醇作为起始材料的碳-碳键形成反应的范围。醇类是最丰富的天然和合成实用的底物，但使用醇的有机合成方法是欠发达的。本研究将开发两种新型的反应歧管，用于不饱和醇和脂肪醇的活化和官能化。这项工作的成功实施可以允许扩大醇的交叉偶联反应性的范围，并为进一步开发醇的合成方法提供框架，所述醇的合成方法可以并入和扩展自由基级联和自由基分选的使用。PI打算成立一个组织，与当地教师一起向代表性不足的群体的学生开展外联活动，提供用品，专业发展和来自不同背景的科学家的研讨会。PI还将与普林斯顿大学的“Chem-STEM外展计划”和科学与工程多样性联盟（ADSE）合作，与当地高中生就STEM职业进行小组讨论。PI还将继续作为计算和实验导师与最初由PI共同创立和共同组织的iCARBON暑期项目合作，为来自全国各地和不同背景的学生提供资源，以虚拟方式参与计算化学研究，该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的学术价值和更广泛的影响审查标准。

Robert T. Martin is awarded an NSF Mathematical and Physical Sciences Ascending Postdoctoral Research Fellowship (NSF MPS-Ascend) to conduct a program of research and activities related to broaden participation by groups underrepresented in STEM. This fellowship to Dr. Martin supports the research project entitled “MPS-Ascend: Development of Selective Reaction Schemes for Photoactivation of Alcohols” under the mentorship of a sponsoring scientist. The host institution for the fellowship is Princeton University, and the sponsoring scientist is Dr. David W. C. MacMillan.This proposal intends to develop organic synthetic methodologies to expand the scope of carbon-carbon bond formation reactions using alcohols as starting materials. Alcohols are among the most naturally abundant and synthetically practical substrates, but organic synthetic methodology using alcohols is underdeveloped. The proposed work will develop two novel reaction manifolds for the activation and functionalization of unsaturated and aliphatic alcohols. Successful implementation of this work may allow for broadening the scope of the cross-coupling reactivity of alcohols and providing a framework for further development of synthetic methodologies for alcohols that can incorporate and expand the use of radical cascades and radical sorting. The PI intends to form an organization that engages in outreach activities to students from underrepresented groups with local teachers to provide supplies, professional development, and seminars from scientists of diverse backgrounds. The PI will also work with the “Chem-STEM Outreach Initiative” and the Alliance for Diversity in Science and Engineering (ADSE) at Princeton University to hold panels and discussions with local high school students about careers in STEM. The PI will also continue working as a computational and experimental mentor with the iCARBON Summer Program initially co-founded and co-organized by the PI, to provide resources to students from across the country and from disparate backgrounds to participate in computational chemical research virtually, without the barrier of meeting in person.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.