The Dynamics of Root Stem Cell Regulation

根干细胞调控的动态

• 批准号: 257393443
• 负责人: Professorin Dr. Yvonne Stahl
• 金额: --
• 依托单位: Institut für Molekulare Biowissenschaften
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2014
• 资助国家: 德国
• 起止时间: 2013-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/257393443?language=en
• 关键词: Dynamics; Root; Stem; Cell; Regulation

Plant roots are essential for overall plant development, growth and performance by providing anchorage in the soil and uptake of nutrients and water. Root stem cell research is needed to address urgent problems faced by our society such as food security and provision of sustainable energy sources. Elucidating the fundamental mechanisms of root meristem maintenance and regulation will provide the basis for translational research from model species such as Arabidopsis thaliana to important crop plants. My aim is to elucidate how intercellular signaling processes in Arabidopsis root stem cell maintenance are mediated and how these affect overall root architecture and development in plants. This will be achieved by utilizing a combination of genetic and advanced fluorescence microscopic techniques to bear on fundamental problems of plant biology.

植物根系通过在土壤中提供锚定并吸收养分和水分，对植物的整体发育、生长和性能至关重要。为了解决粮食安全和可持续能源供应等社会面临的紧迫问题，需要进行根干细胞研究。阐明根分生组织维持和调控的基本机制将为拟南芥等模式物种向重要作物植物的转化研究提供基础。我的目的是阐明在拟南芥根干细胞维持中的细胞间信号过程是如何介导的，以及这些过程如何影响植物的整体根结构和发育。这将通过利用遗传和先进的荧光显微技术的结合来解决植物生物学的基本问题来实现。