The Dynamics of Root Stem Cell Regulation

植物根对植物的整体发育、生长和表现至关重要，因为它在土壤中提供锚定，并吸收养分和水分。需要对根干细胞进行研究，以解决我们社会面临的紧迫问题，如粮食安全和提供可持续能源。阐明根分生组织维持和调控的基本机制将为从拟南芥等模式植物到重要作物的转译研究提供基础。我的目的是阐明拟南芥根干细胞维持中的细胞间信号过程是如何介导的，以及这些过程如何影响植物的整体根构型和发育。这将通过利用遗传学和先进的荧光显微技术相结合来实现，以解决植物生物学的基本问题。

Plant roots are essential for overall plant development, growth and performance by providing anchorage in the soil and uptake of nutrients and water. Root stem cell research is needed to address urgent problems faced by our society such as food security and provision of sustainable energy sources. Elucidating the fundamental mechanisms of root meristem maintenance and regulation will provide the basis for translational research from model species such as Arabidopsis thaliana to important crop plants. My aim is to elucidate how intercellular signaling processes in Arabidopsis root stem cell maintenance are mediated and how these affect overall root architecture and development in plants. This will be achieved by utilizing a combination of genetic and advanced fluorescence microscopic techniques to bear on fundamental problems of plant biology.