I-Corps: A magnetic resonance-compatible touchscreen with video display

I-Corps项目更广泛的影响/商业潜力是开发一种无药物策略，以减轻磁共振成像（MRI）期间的焦虑。目前的一种解决方案是镇静，然而，许多反对MRI的患者也反对镇静。因此，许多患者选择避免核磁共振成像程序，即使建议有效的医学治疗。该提议的技术是一种与MRI兼容的数字平板电脑，可以为患者在MRI期间提供数字触摸屏访问他们的智能手机，以减轻焦虑而无需镇静。MRI外围设备领域是一个新兴领域，为患者提供MRI扫描期间使用的MRI兼容设备。目前，MRI外围设备仅限于通常用于安全或身体舒适的基本设备，如按钮和坐垫。此外，这项技术可以被研究人员用来扩大对人类大脑功能的研究范围。拟议的数字平板电脑为研究人员提供了一种多功能的交互式MRI外围设备，可以提供涉及复杂动作的各种实验操作。拟议的技术可以通过减少患者对必要医疗程序的厌恶来增加患者的健康结果，并扩大人类大脑功能基础研究的范围。I-Corps项目的基础是开发一种互动式数字平板电脑，供患者和研究参与者在接受磁共振成像（MRI）扫描时使用。提出的技术使用特殊的信号驱动电路和屏蔽，在MRI所需的强电磁场中安全工作，而不会影响所获得的图像质量。显示和触摸传感技术的空间和时间分辨率与当前最先进的数字平板电脑和智能手机相当，即使在儿科成像中也可以实现无缝交互。此外，拟议的数字平板电脑在研究人类大脑功能方面比现有技术有优势，可以接收输入（例如，按下按钮），但不能产生输出（例如，显示屏幕上的图像）。研究表明，与其他现有解决方案相比，在人类大脑功能研究中使用拟议的技术在几个大脑区域产生了显着不同的大脑功能。数字平板电脑为研究人员提供了一种设备，可以在参与者进行MRI扫描时在MRI的圆柱体内接收输入并提供输出，从而拓宽了人类大脑的研究，支持更多种类的动作，例如手写/绘画、平板电脑使用以及个人智能手机使用。所提出的数字片剂可用于减少患者在临床MRI过程中的焦虑和在MRI研究中研究脑功能。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

The broader impact/commercial potential of this I-Corps project is the development of a drug-free strategy for alleviating anxiety during magnetic resonance imaging (MRI). One current solution is sedation, however, many patients who are averse to MRI are also averse to sedation. Consequently, many patients choose to avoid MRI procedures, even when recommended for effective medical treatment. The proposed technology is an MRI-compatible digital tablet that may provide patients with digital touchscreen access to their smartphones during MRI to alleviated anxiety without sedation. The field of MRI peripherals is an emerging field that provides MRI-compatible devices for patients to use during an MRI scan. Currently, MRI peripherals are limited to basic devices that are generally used for safety or physical comfort, such as button presses and cushions. Additionally, this technology may be used by researchers to expand the scope of research on human brain function. The proposed digital tablet offers researchers a versatile, interactive MRI peripheral that may deliver a wide variety of experimental manipulations involving complex actions. The proposed technology may increase patient health outcomes by reducing patient aversion to necessary medical procedures and expand the scope of basic research on human brain function.This I-Corps project is based on the development of an interactive digital tablet that may be used by patients and research participants while undergoing magnetic resonance imaging (MRI) scanning. The proposed technology uses special signal-driver circuitry and shielding to safely function in the strong electromagnetic fields required for MRI without impacting the quality of the images acquired. The spatial and temporal resolution of the display and touch-sensing technology is on par with current state-of-the-art digital tablets and smartphones, allowing for seamless interactions even in pediatric imaging. Additionally, the proposed digital tablet provides an advantage over current technology for studies of human brain function that can receive input (e.g., a button press) but cannot generate output (i.e., images on a display screen). Research has demonstrated that using the proposed technology in studies of human brain function produced significantly different brain function in several brain regions when compared to other current solutions. The digital tablet broadens human brain research by providing researchers with a device that can receive input and provide output within the cylinder of the MRI while a participant is undergoing MRI scanning, supporting a much larger variety of actions, such as handwriting/drawing and tablet use as well as personal smartphone use. The proposed digital tablet may have application for reducing patient anxiety during clinical MRI procedures and for studying brain function in MRI research.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.