Interplay between orientation and lift forces on non-spherical particles in complex fluids

复杂流体中非球形颗粒的方向力和升力之间的相互作用

基本信息

  • 批准号:
    2341154
  • 负责人:
  • 金额:
    $ 45万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2024
  • 资助国家:
    美国
  • 起止时间:
    2024-04-15 至 2027-03-31
  • 项目状态:
    未结题

项目摘要

Viscoelastic suspensions are polymeric fluids containing particles. These systems are everywhere in our daily lives, for example, found in foods, consumer products, coatings, adhesives, and pastes (e.g., 3D printing). These systems are also common in biological fluids (e.g., mucous, blood, bacterial suspensions). One interesting feature of viscoelastic suspensions is that particles in such fluids acquire lift forces during pressure-driven flows that drive them toward specific regions in the fluid. This phenomenon is important in polymer processing because it determines the final structure of the materials. It is also important in microfluidic technologies where flow is used to separate biological suspensions by particle size and shape. While the lift forces are well-studied for spherical particles, little is known about how particle shape affects the lift because the phenomenon is highly coupled to the particle orientation, which itself is a function of the flow. This award will perform experiments, simulations, and theories to characterize the motion of non-spherical particles in polymeric fluids and quantify the coupling between the lift and orientation for different flow rates, particle geometries, fluid properties, and channel confinement. This information is valuable for processing rod-like and disk-like particles in viscoelastic suspensions in the applications mentioned above, as it provides design guidelines for the migration time and final location for different particle shapes.This study specifically will perform microfluidic experiments where one flows a dilute suspension of spheroids (prolate and oblate) through a tube. Different fluids and channel sizes will be used, allowing one to systematically vary the fluid properties and channel confinement. The particle’s 3D position and orientation distribution at different channel locations will be visualized using holography, allowing one to obtain long-time particle positions and rate of migration. Direct numerical simulations and theories will complement the studies, developing relationships for lift forces in this geometry as well as other geometries that are important for fluid characterization. Both investigators will create demos about complex fluids for Purdue’s Women in Engineering Program, as well as create similar exhibits for elementary school students at Imagination Station, a local science center. These exhibits will be run by undergraduates working in the respective labs and an honors engineering society advised by the investigators. Lastly, undergraduates from underrepresented communities will be recruited for research through Purdue’s SURF program.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
粘弹性悬浮液是含有颗粒的聚合物流体。 这些系统在我们的日常生活中无处不在,例如,在食品、消费品、涂料、粘合剂和糊剂(例如,3D打印)。 这些系统在生物流体中也很常见(例如,粘液、血液、细菌悬浮液)。 粘弹性悬浮液的一个有趣的特征是,在这种流体中的颗粒在压力驱动的流动期间获得升力,该压力驱动的流动将颗粒推向流体中的特定区域。 这种现象在聚合物加工中很重要,因为它决定了材料的最终结构。 它在微流体技术中也很重要,其中流动用于通过颗粒尺寸和形状分离生物悬浮液。 虽然对球形颗粒的升力进行了充分的研究,但对颗粒形状如何影响升力知之甚少,因为这种现象与颗粒取向高度相关,而颗粒取向本身是流动的函数。该奖项将进行实验,模拟和理论,以表征聚合物流体中非球形颗粒的运动,并量化不同流速,颗粒几何形状,流体特性和通道限制的升力和方向之间的耦合。这一信息是有价值的处理棒状和盘状颗粒在粘弹性悬浮液中的上述应用,因为它提供了设计指南的迁移时间和最终位置为不同的颗粒形状。这项研究将具体进行微流控实验,其中一个流动的稀释悬浮液的球状体(长球形和扁球形)通过一个管。将使用不同的流体和通道尺寸,允许系统地改变流体性质和通道限制。粒子在不同通道位置的3D位置和取向分布将使用全息术可视化,允许获得长时间粒子位置和迁移速率。直接的数值模拟和理论将补充研究,发展升力在这种几何形状以及其他几何形状,是重要的流体特性的关系。 两位研究人员将为普渡大学的女性工程项目制作关于复杂流体的演示,并为当地科学中心想象站的小学生制作类似的展览。 这些展览将由在各自实验室工作的本科生和由调查人员建议的荣誉工程学会管理。最后,来自代表性不足的社区的本科生将通过普渡大学的SURF计划被招募进行研究。该奖项反映了NSF的法定使命,并通过使用基金会的智力价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

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Vivek Narsimhan其他文献

Comparison of vial heat transfer coefficients during the primary and secondary drying stages of freeze-drying
  • DOI:
    10.1016/j.ijpharm.2023.122746
  • 发表时间:
    2023-03-25
  • 期刊:
  • 影响因子:
  • 作者:
    Kyu Yoon;Vivek Narsimhan
  • 通讯作者:
    Vivek Narsimhan
Randomized-field microwave-assisted pharmaceutical lyophilization with closed-loop control
带闭环控制的随机场微波辅助制药冻干
  • DOI:
    10.1038/s41598-025-91642-4
  • 发表时间:
    2025-03-27
  • 期刊:
  • 影响因子:
    3.900
  • 作者:
    Alina A. Alexeenko;Ahmad Darwish;Drew Strongrich;Petr Kazarin;Chanakya Patil;Cole W. Tower;Isaac S. Wheeler;Eric Munson;Qi Zhou;Vivek Narsimhan;Kyu Yoon;Steven L. Nail;Anthony Cofer;Justin Stanbro;Harshil Renawala;Daniel Roth;Francis DeMarco;Justin Griffiths;Dimitrios Peroulis
  • 通讯作者:
    Dimitrios Peroulis

Vivek Narsimhan的其他文献

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{{ truncateString('Vivek Narsimhan', 18)}}的其他基金

Collaborative Research: Dynamics and Stability of Multi-Component Lipid Vesicles in Flow
合作研究:多组分脂质囊泡流动的动力学和稳定性
  • 批准号:
    2147559
  • 财政年份:
    2022
  • 资助金额:
    $ 45万
  • 项目类别:
    Standard Grant
Brownian bridges for stochastic problems in chemical sciences
化学科学中随机问题的布朗桥
  • 批准号:
    2126230
  • 财政年份:
    2021
  • 资助金额:
    $ 45万
  • 项目类别:
    Standard Grant

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An Examination of the Bidirectional and Contextual Relationship between Critical Consciousness and Wellbeing Among Minoritized Emerging Adults
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