Channeling Excited States Towards New Productive Photochemical Pathways

在化学结构、动力学和机制B(CSDM-B)计划的支持下，鲍林格林州立大学的Jayaraman Sivan uru教授和他的团队致力于发现选择性修改化学结构所产生的新的和富有成效的光化学途径。这些新的光反应被设计用于可持续的化学合成。光化学是一门研究化学反应的科学，这些化学反应是由光引发的，并通过高能激发态进行。拟议的调查将使学生能够培训与光化学、光物理和物理有机化学有关的概念，并在智力上影响他们对合成、纳米科学和材料科学的理解。这项研究计划通过参与和合作，将科学研究与教育培训和推广相结合。西瓦鲁鲁教授和他的团队将继续从事各种超越学术和科学培训的外展活动。这些外展活动包括野餐(家长参与儿童，培养对科学的好奇心)计划，以及通过周六研讨会系列吸引社区参与，该系列研讨会在国内和国际上都有影响。野餐计划是与俄亥俄州西北部的高中合作进行的，通过暑期实习吸引高中生，对他们的本科职业生涯产生积极影响。该项目致力于通过发现新的光化学反应来培养创造力。为此，将通过利用光化学原理引导激发态反应性，以(I)发现光反应特有的新的反应性；(Ii)利用现代光化学/光物理工具，努力发展关于激发态过程的全面知识；以及(Iii)探索激发态动力学和寿命以及瞬变中间体稳定性的重要性。结构修饰的目的是发现新的光反应性，实现区域、立体和化学选择性，并导致更全面的机理模型。所有上述策略都试图发现新的激发态途径/反应性，它们都建立在公认的光化学原理基础上。实现拟议策略的全部潜力依赖于将激发态的动力学和寿命之间的微妙平衡与作为反应的光化学控制的分子特征并列在一起。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

With support from the Chemical Structure, Dynamics and Mechanism-B (CSDM-B) program, Professor Jayaraman Sivaguru and his group at Bowling Green State University aim to discover new and productive photochemical pathways which result from the selective modification of chemical structure. These new photoreactions are designed to have applications in sustainable chemical synthesis. Photochemistry is the science of chemical reactions that are initiated by light, and which proceed through highly energetic excited states. The proposed investigations will enable training of students in concepts related to photochemistry, photophysics and physical organic chemistry and intellectually impact their understanding related to synthesis, nanoscience, and materials science. This research program integrates scientific research with educational training and outreach through engagement and collaboration. Professor Sivaguru and his team will continue to engage in a myriad of outreach activities that go beyond academics and scientific training. These outreach activities include the PICNICS (Parents Involvement with Children, Nurturing Intellectual Curiosity in Science) program, and engaging the community through the Saturday Seminar Series that has both national and international reach. The PICNICS program is conducted in collaboration with northwest Ohio high schools, engaging high school students through summer internships to positively influence their undergraduate career path.This project aspires to foster creativity by uncovering new photochemical reactions. This will be done by channeling excited state reactivity through the exploitation of photochemical principles to (i) uncover novel reactivity that is unique to photoreactions; (ii) employ modern photochemical/photophysical tools to in an effort to develop comprehensive knowledge about excited state processes; and (iii) explore the importance of dynamics and lifetimes of excited states, as well as the stability of transient intermediates. Structural modification is designed to uncover new photoreactivity, achieve regio-, stereo- and chemoselectivity and lead to a more comprehensive mechanistic model. All the above strategies seek to unearth new excited state pathways/reactivity are grounded in well- established photochemical principles. Realizing the full potential of the proposed strategies rely on juxtaposing the delicate balance between dynamics and lifetimes of the excited states with molecular features that transpire as photochemical control of reactivity.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.