Channeling Excited States Towards New Productive Photochemical Pathways

在化学结构、动力学和机理- b （CSDM-B）项目的支持下，鲍灵格林州立大学的Jayaraman Sivaguru教授和他的团队致力于发现新的、高效的光化学途径，这些途径是由化学结构的选择性修饰引起的。这些新的光反应被设计用于可持续的化学合成。光化学是研究由光引发的化学反应的科学，这些反应经过高能量的激发态。拟议的调查将使学生在光化学，光物理和物理有机化学相关概念的培训，并在智力上影响他们对合成，纳米科学和材料科学的理解。该研究项目通过参与和合作，将科学研究与教育培训和推广相结合。Sivaguru教授和他的团队将继续参与无数超越学术和科学培训的外展活动。这些拓展活动包括野餐（父母与孩子的参与，培养对科学的求知欲）计划，以及通过全国性和国际范围的周六系列研讨会吸引社区参与。野餐计划是与俄亥俄州西北部的高中合作开展的，通过暑期实习吸引高中生，对他们的本科职业道路产生积极影响。该项目旨在通过发现新的光化学反应来培养创造力。这将通过利用光化学原理来引导激发态反应来完成：(i)发现光反应特有的新反应性；（ii）运用现代光化学/光物理工具，努力发展有关激发态过程的全面知识；(3)探讨激发态的动力学和寿命的重要性，以及瞬态中间体的稳定性。结构修饰旨在揭示新的光反应性，实现区域、立体和化学选择性，并导致更全面的机理模型。所有上述策略都是基于完善的光化学原理，寻求发现新的激发态途径/反应性。实现所提出的策略的全部潜力依赖于并置激发态的动力学和寿命之间的微妙平衡，以及作为光化学控制反应性而发生的分子特征。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

With support from the Chemical Structure, Dynamics and Mechanism-B (CSDM-B) program, Professor Jayaraman Sivaguru and his group at Bowling Green State University aim to discover new and productive photochemical pathways which result from the selective modification of chemical structure. These new photoreactions are designed to have applications in sustainable chemical synthesis. Photochemistry is the science of chemical reactions that are initiated by light, and which proceed through highly energetic excited states. The proposed investigations will enable training of students in concepts related to photochemistry, photophysics and physical organic chemistry and intellectually impact their understanding related to synthesis, nanoscience, and materials science. This research program integrates scientific research with educational training and outreach through engagement and collaboration. Professor Sivaguru and his team will continue to engage in a myriad of outreach activities that go beyond academics and scientific training. These outreach activities include the PICNICS (Parents Involvement with Children, Nurturing Intellectual Curiosity in Science) program, and engaging the community through the Saturday Seminar Series that has both national and international reach. The PICNICS program is conducted in collaboration with northwest Ohio high schools, engaging high school students through summer internships to positively influence their undergraduate career path.This project aspires to foster creativity by uncovering new photochemical reactions. This will be done by channeling excited state reactivity through the exploitation of photochemical principles to (i) uncover novel reactivity that is unique to photoreactions; (ii) employ modern photochemical/photophysical tools to in an effort to develop comprehensive knowledge about excited state processes; and (iii) explore the importance of dynamics and lifetimes of excited states, as well as the stability of transient intermediates. Structural modification is designed to uncover new photoreactivity, achieve regio-, stereo- and chemoselectivity and lead to a more comprehensive mechanistic model. All the above strategies seek to unearth new excited state pathways/reactivity are grounded in well- established photochemical principles. Realizing the full potential of the proposed strategies rely on juxtaposing the delicate balance between dynamics and lifetimes of the excited states with molecular features that transpire as photochemical control of reactivity.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.