Light Induced Enantiospecific Chiral Transfer In Solution

基于化学结构、动力学和机制计划（CSDM）的资助，北达科他州州立大学化学和生物化学系的Sivaguru Jayaraman教授的小组将开展有关溶液中光诱导的对映体特异性手性转移的研究。在光诱导转化过程中合成具有高立体选择性的手性化合物为开发对环境影响最小的可持续策略提供了机会。作为研究的一部分，PI将寻求光反应中立体控制的新策略，以获得对光与物质相互作用的基本理解，以及对分子反应性，动力学和非键相互作用的复杂控制，以增强光产物的立体选择性。项目开发计划无缝集成了科学研究，教育培训和公众宣传。参与拟议调查的学生将学习传统技术来表征和评估对映体特异性光转化过程中的不对称诱导，以及现代光谱方法和表征技术来评估激发态反应性。PI计划通过他在北达科他州开发的PICNICS（父母参与儿童，培养科学知识）外展计划吸引当地高中生。该推广计划的目的是通过鼓励高中生将科学和数学作为职业道路，为他们提供一个前沿的研究环境。

Based on the funding from Chemical Structure, Dynamics and Mechanism Program (CSDM) program, Prof. Sivaguru Jayaraman's group at the Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND will carry out studies pertaining to light induced enantiospecific chiral transfer in solution. Synthesizing chiral compounds with high stereoselectivity during light induced transformations provides an opportunity to develop sustainable strategies with minimal impact on the environment. As part of the investigation the PI will pursue new strategies for stereocontrol in photoreactions to gain a fundamental understanding of interaction of light with matter coupled with an intricate control over molecular reactivity, dynamics and non-bonding interactions to enhance stereoselectivity in the photoproducts.The project development plan seamlessly integrates scientific research, educational training, and public outreach. Students involved in the proposed investigations will learn both traditional techniques to characterize and evaluate asymmetric induction during enantiospecific phototransformations and modern spectroscopic methods and characterization techniques to assess excited state reactivity. The PI plans to engage local high school students through the PICNICS (Parents Involvement with Children, Nurturing Intellectual Curiosity in Science) outreach program that he has developed at North Dakota. The aim of the outreach program is to provide a cutting edge research environment to high school students there by encouraging them to look up to science and math as career paths.