Coordination Funds

协调基金

• 批准号: 265970916
• 负责人: Professor Dr.-Ing. Georg Duda
• 金额: --
• 依托单位: Julius Wolff Institut für Biomechanik und Muskuloskeletale Regeneration (CVK)
• 依托单位国家: 德国
• 项目类别: Research Units
• 财政年份: 2014
• 资助国家: 德国
• 起止时间: 2013-12-31 至 2021-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/265970916?language=en
• 关键词: Coordination; Funds

We intend to structure the activities in the TP Z towards: (a) coordinating the animal models used in the Research Unit to enable better comparability; (b) raising public awareness of musculoskeletal regeneration with respect to aging, immunological fitness and mechanical adaptability; (c) structuring of education by using the infrastructure of the Berlin-Brandenburg School for Regenerative Therapies specifically for clinical scientists (GEROK), and (d) continuation of the international scientific networking activities that have been developed among the participants of the proposed Research Unit during their previous work in order to emphasize the importance of investigating the influence of aging on regeneration. To validate findings from mouse models in human patients, access to qualified human hematomas is essential. Thus a special feature will be the access to harvested human hematoma from fracture patients within specified age groups. The harvesting will be coordinated with the help of the BCRT core unit ¿cell harvest¿. All hematomas will be prepared for analysis, stored and made available for the different groups to provide them with human sample data that serve as correlate to findings in hematoma and tissue of the mouse models within the Research Unit.

我们打算将TP Z的活动结构化，以实现：（a）协调研究单位使用的动物模型，以实现更好的可比性;（B）提高公众对肌肉骨骼再生与衰老、免疫适应性和机械适应性的认识;（c）利用柏林-勃兰登堡再生疗法学院专门为临床科学家提供的基础设施，构建教育结构，及（d）继续在拟设研究组的参与者之间开展国际科学网络活动，这些活动是在他们以前的工作中开展的，目的是强调调查衰老对再生的影响的重要性。为了验证人类患者小鼠模型的结果，获得合格的人类血肿是必不可少的。因此，一个特殊的功能将是获取指定年龄组内骨折患者的人体血肿。收获将在BCRT核心单元细胞收获的帮助下进行协调。将准备所有血肿以供分析、储存并提供给不同组，以向其提供与研究单位内小鼠模型的血肿和组织中的发现相关的人类样本数据。