Nuclear structure and function in the nucleated planctomycete bacterium Gemmata obscuriglobus: a third cell plan for living organisms?

有核浮菌菌 Gemmata obscuriglobus 的核结构和功能：活生物体的第三种细胞计划？

• 批准号: DP0881485
• 负责人: Prof John Fuerst
• 金额: $ 17.7万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0881485
• 关键词: Nuclear; structure; function; nucleated; planctomycete

The project will contribute knowledge of how cells such as those of animals and plants evolved from bacterial components. Origins of cell nuclei and pores in nuclear membranes will be studied via the simple eukaryote-like nucleus of the planctomycete Gemmata obscuriglobus, from Australian freshwater. Simple nuclear pore-like structures of G. obscuriglobus will help understanding nucleus function in animal cells, and such pores will give insight into 'minimal' composition needed for cell nuclei, and allow design of biological nanopores. The origin of the nucleus is a major problem in biology, and an Australian contribution to its solution will achieve international recognition.

该项目将贡献有关动物和植物细胞等细胞如何从细菌成分进化而来的知识。细胞核和核膜孔的起源将通过来自澳大利亚淡水的浮菌Gemmata obscuriglobus的简单真核细胞核进行研究。 G. obscuriglobus 的简单核孔状结构将有助于了解动物细胞的细胞核功能，并且此类孔将深入了解细胞核所需的“最小”组成，并允许设计生物纳米孔。 细胞核起源是生物学中的一个重大问题，澳大利亚对其解决方案的贡献将获得国际认可。