Synthesis of boronic ester cages with dimensions in the nanometer regime by dynamic covalent chemistry

通过动态共价化学合成纳米尺寸的硼酸酯笼

• 批准号: 273746011
• 负责人: Professor Dr. Michael Mastalerz
• 金额: --
• 依托单位: Organisch-Chemisches Institut
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2015
• 资助国家: 德国
• 起止时间: 2014-12-31 至 2019-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/273746011?language=en
• 关键词: Synthesis; boronic; ester; cages; dimensions

The projects objective is to get a deeper insight into the synthesis of hape-persistent sthree-dimensional organic cage compounds on the basis of the formation of boronic esters. The influence of constitutional and geometrically structural diffeerences of the used tetraoles on the formation of cage compounds and theitr dimers will be investigated. Depending on the geometries of the used tetraoles, cages with archimedian or platonic shape are accessible, with inner diameters up to 5 nm. The dynamic exchange of precursor molecules will be investigated too, as well as a poststabilisation of the cages by the formation of multiple C-C bonds in the outer sphere.

本项目的目标是在硼酸酯合成的基础上，更深入地研究具有形状稳定性的三维有机笼状化合物的合成。研究了四元环的结构和几何构型对笼状化合物及其二聚体形成的影响。根据所使用的四醇的几何形状，可以使用阿基米德或柏拉图形状的笼，内径高达5 nm。 也将研究前体分子的动态交换，以及通过在外层形成多个C-C键来后稳定笼。