Development of Pyrrolopyrimidines as Inhibitors of ATP-Binding Proteins

作为 ATP 结合蛋白抑制剂的吡咯并嘧啶的开发

• 批准号: DP0770653
• 负责人: Prof Jonathan Morris
• 金额: $ 15.91万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0770653
• 关键词: Development; Pyrrolopyrimidines; Inhibitors; ATP; Binding

This project seeks to generate analogues of natural products that have been found to be active against cancer cells and tropical parasites. The new materials produced by this project will aid in the study of biochemical processes involved in diseases such as cancer and lymphatic filariasis, thus leading the way to development of these compounds as potential treatments for such diseases.

该项目寻求产生已被发现对癌细胞和热带寄生虫具有活性的天然产品的类似物。该项目生产的新材料将有助于研究癌症和淋巴丝虫病等疾病所涉及的生化过程，从而引领这些化合物作为此类疾病的潜在治疗方法的开发。