Is placental aging the key to understanding, predicting and preventing stillbirth?

胎盘老化是理解、预测和预防死产的关键吗？

• 批准号: nhmrc : 1084782
• 负责人: Prof Jonathan Morris
• 金额: $ 31.6万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/placental-aging-key-preventing-stillbirth/519032
• 关键词: placental; aging; key; understanding; predicting

Stillbirth occurs in 35 times as many pregnancies as sudden infant death but the causes are unknown. This project will help to develop tests that can predict the risk of stillbirth so that the obstetrician can deliver the baby before it dies. The investigators hypothesise that stillbirth is due to aging of the placenta and that markers of the aging placenta can be detected in the mother’s blood. The project brings together experts in the placenta, aging and obstetric care of high risk pregnancy.

死产的发生率是婴儿猝死的35倍，但原因不明。该项目将有助于开发能够预测死产风险的测试，以便产科医生能够在婴儿死亡之前将其接生。研究人员假设死产是由于胎盘老化，并且可以在母亲的血液中检测到老化胎盘的标记物。该项目汇集了胎盘、衰老和高危妊娠产科护理方面的专家。