Reversible Single-Chain Folding of Macromolecules via Non-Covalent Interactions (A01)

与至少部分了解的多肽折叠成蛋白质相反，对聚合物折叠成单链纳米颗粒（SCNP）的机械原理的了解仍处于起步阶段。复杂的大分子与几个新的共价和非共价（光化学控制）的折叠点将探讨和他们的压缩详细研究在原子水平上使用各种复杂的NMR光谱方法。

In contrast to the at least partially understood folding of polypeptides to proteins, the understanding of the mechanistic principles of the folding of polymers into single chain nanoparticles (SCNPs) is still in its infancy. Complex macromolecules with several novel covalent and non-covalent (photochemically controlled) folding points will be explored and their compaction studied in detail on an atomistic level using a variety of sophisticated NMR-spectroscopic methods.