Proteomanalytik und Massenspektrometrie (B16*)

这个项目旨在描述决策背后的感觉皮质值计算。通过结合动物行为的多通道记录和人类的脑磁图记录，我们将研究神经元振荡中的值表征的时间动力学，既在受限的局部电路水平上，也在整个新皮质分布的更大规模的活动模式上。药理学操作将被用来测试这些价值表征的动态基础上的候选机制。最后，通过将类似的计算模型应用于啮齿动物和人类数据集，我们将能够描述自适应值表示和选择的共同功能原则。

This project aims at characterising sensory cortical value computations underlying decision making. By combining multichannel recordings in behaving animals and MEG recordings in humans we will investigate the temporal dynamics of value representations in neuronal oscillations both at the level of circumscribed local circuits and larger-scale patterns of activity distributed across the entire neocortex. Pharmacological manipulations will be used to test candidate mechanisms underlying the dynamics of these value representations. Finally, by applying similar computational models to both the rodent and human data sets we will be able to describe common functional principles of adaptive value representations and choice.