Analysis of the fundamentals of the cell structure formation while direct freeze foaming of biocom-patible ceramic foams

生物相容性陶瓷泡沫直接冷冻发泡过程中泡孔结构形成的基本原理分析

• 批准号: 310892168
• 负责人: Professor Dr.-Ing. Maik Gude
• 金额: --
• 依托单位: Fraunhofer-Institut für Keramische Technologien und Systeme (IKTS)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2016
• 资助国家: 德国
• 起止时间: 2015-12-31 至 2021-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/310892168?language=en
• 关键词: Analysis; fundamentals; cell; structure; formation

Frozen foams are novel and innovative cellular structures based on a direct foaming process that can be produced from any material that can be processed by powder technology. The foam production process is influenced by a very complex interaction of various process and material parameters, which were previously chosen purely empirically and were also difficult to reproduce. For the targeted and application-oriented design of properties, it is necessary to investigate phenomena occurring during foam formation and the effect of relevant process and material parameters on the structural properties in order to derive manufacturing and quality guidelines (e.g. mechanical strength, cell/pore sizes, pore size distribution). The possible applications of such foam structures cover a very large field and range from biomedical applications (e.g. bone substitute or cell aeration material) to carriers for catalysts, biosensors or pharmaceuticals to heat and noise insulating materials. The diversity of these applications results from the range of possible starting suspensions and above all from the process parameter-dependent foam structure properties, such as the cell geometry, the cell size distribution, the proportions of open and closed cells as well as the composition of the cell webs.In the finished first phase (grant number 310892168) it was possible to achieve a deeper understanding of the principles of freeze foam structure formation by analyzing the influence of selected suspension and process parameters on relevant structural properties of biocompatible ceramic foams. On the basis of the knowledge acquired, the focus of the continuation of the project is on the targeted adjustment and tailoring of the macrostructure (homogenization of the pore size/distribution in the foam cells) and the microstructure (influencing and control of freezing structures in the web pores) to produce ceramic foams suitable for stress and application.

冷冻泡沫是基于直接发泡工艺的新颖和创新的蜂窝结构，可以由任何可以通过粉末技术加工的材料生产。泡沫生产过程受到各种工艺和材料参数的非常复杂的相互作用的影响，这些参数以前是纯粹凭经验选择的，也很难重现。对于有针对性和面向应用的性能设计，有必要研究泡沫形成过程中发生的现象以及相关工艺和材料参数对结构性能的影响，以获得制造和质量指南（例如机械强度，单元/孔径，孔径分布）。这种泡沫结构的可能应用覆盖了非常大的领域，并且范围从生物医学应用（例如骨替代物或细胞通气材料）到催化剂、生物传感器或药物的载体到隔热和隔音材料。这些应用的多样性来自于可能的起始悬浮液的范围，尤其是来自于依赖于工艺参数的泡沫结构性质，例如泡孔几何形状、泡孔尺寸分布，开孔和闭孔的比例以及孔网的组成。在完成的第一阶段中，（授权号310892168）通过分析所选悬浮液和工艺参数对生物相容性陶瓷泡沫体的相关结构性质的影响，可以实现对冷冻泡沫体结构形成原理的更深入理解。在所获得知识的基础上，继续开展该项目的重点是有针对性地调整和定制宏观结构（泡沫细胞中孔径/分布的均匀化）和微观结构（影响和控制腹板孔中的冻结结构），以生产适合应力和应用的陶瓷泡沫。