Analysis of the fundamentals of the cell structure formation while direct freeze foaming of biocom-patible ceramic foams

生物相容性陶瓷泡沫直接冷冻发泡过程中泡孔结构形成的基本原理分析

• 批准号: 310892168
• 负责人: Professor Dr.-Ing. Maik Gude
• 金额: --
• 依托单位: Fraunhofer-Institut für Keramische Technologien und Systeme (IKTS)
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2016
• 资助国家: 德国
• 起止时间: 2015-12-31 至 2021-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/310892168?language=en
• 关键词: Analysis; fundamentals; cell; structure; formation

Frozen foams are novel and innovative cellular structures based on a direct foaming process that can be produced from any material that can be processed by powder technology. The foam production process is influenced by a very complex interaction of various process and material parameters, which were previously chosen purely empirically and were also difficult to reproduce. For the targeted and application-oriented design of properties, it is necessary to investigate phenomena occurring during foam formation and the effect of relevant process and material parameters on the structural properties in order to derive manufacturing and quality guidelines (e.g. mechanical strength, cell/pore sizes, pore size distribution). The possible applications of such foam structures cover a very large field and range from biomedical applications (e.g. bone substitute or cell aeration material) to carriers for catalysts, biosensors or pharmaceuticals to heat and noise insulating materials. The diversity of these applications results from the range of possible starting suspensions and above all from the process parameter-dependent foam structure properties, such as the cell geometry, the cell size distribution, the proportions of open and closed cells as well as the composition of the cell webs.In the finished first phase (grant number 310892168) it was possible to achieve a deeper understanding of the principles of freeze foam structure formation by analyzing the influence of selected suspension and process parameters on relevant structural properties of biocompatible ceramic foams. On the basis of the knowledge acquired, the focus of the continuation of the project is on the targeted adjustment and tailoring of the macrostructure (homogenization of the pore size/distribution in the foam cells) and the microstructure (influencing and control of freezing structures in the web pores) to produce ceramic foams suitable for stress and application.

冷冻泡沫是基于直接泡沫过程的新颖而创新的细胞结构，可以用粉末技术处理的任何材料产生。泡沫生产过程受到各种过程和材料参数的非常复杂的相互作用的影响，这些过程以前纯粹是经验选择的，也很难再现。对于针对性和面向应用的性质设计，有必要研究泡沫形成过程中发生的现象以及相关过程和材料参数对结构特性的影响，以得出制造和质量指南（例如机械强度，细胞/孔径，细胞/孔径，孔径，孔径分布）。此类泡沫结构的可能应用涵盖了很大的领域和范围，从生物医学应用（例如骨骼替代或细胞曝气材料）到载体，生物传感器或药品到载热和噪声绝缘材料。这些应用的多样性源于可能的起始悬架范围，最重要的是，依赖于过程参数依赖的泡沫结构属性，例如细胞几何形状，细胞大小分布，开放和封闭的单元格的比例以及细胞网的组成以及完成的第一阶段的组成。生物相容性陶瓷泡沫的相关结构特性的过程参数。根据获取的知识，该项目的延续的重点是宏观结构的靶向调整和调整（泡沫细胞中孔径/分布的均质化）和微观结构（影响和控制网络孔中的冷冻结构），以产生适合压力和应用的陶瓷泡沫。