Importance of abdominal organ congestion and hypoperfusion in patients with heart failure, and association with hepatkine

心力衰竭患者腹部器官充血和灌注不足的重要性及其与肝因子的关系

• 批准号: 20K16529
• 负责人: Ichijo Yasuhiro
• 金额: $ 2.41万
• 依托单位: Fukushima Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2020
• 资助国家: 日本
• 起止时间: 2020-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-20K16529/
• 关键词: 心不全; 多臓器連関; 腹部超音波検査; ヘパトカイン; 腹部超音波; 臓器障害

项目成果

Serum hepatokine selenoprotein P is upregulated by hepatic hypoperfusion and predicts adverse prognosis in heart failure patients.

血清肝因子硒蛋白 P 因肝脏灌注不足而上调，可预测心力衰竭患者的不良预后。

• 发表时间: 2020
• 作者: Misaka T;Ichijo Y;Yoshihisa A;Hotsuki Y;Watanabe K;Sato Y;Kimishima Y;Yokokawa T;Oikawa M;Kobayashi A;Takeishi Y.
• 通讯作者: Takeishi Y.

Intrarenal Doppler ultrasonography reflects hemodynamics and predicts prognosis in patients with heart failure.

肾内多普勒超声检查反映了心力衰竭患者的血液动力学并预测预后。

• DOI: 10.1038/s41598-020-79351-6
• 发表时间: 2020-12-17
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Yoshihisa A;Watanabe K;Sato Y;Ishibashi S;Matsuda M;Yamadera Y;Ichijo Y;Yokokawa T;Misaka T;Oikawa M;Kobayashi A;Takeishi Y
• 通讯作者: Takeishi Y

Decrease in hepatokine fetuin-a is associated with hepatic hypoperfusion in patients with heart failure.

肝因子胎球蛋白-a 的减少与心力衰竭患者的肝脏灌注不足有关。

• 发表时间: 2021
• 作者: Tomita Y;Misaka T;Yoshihisa A;Ichijo Y;Anzai F;Ohara H;Sugawara Y;Hotsuki Y;Watanabe K;Sato Y;Oikawa M;Kobayashi A;Takeishi Y
• 通讯作者: Takeishi Y

Decreases in hepatokine Fetuin-A levels are associated with hepatic hypoperfusion and predict cardiac outcomes in patients with heart failure. (In press)

肝因子胎球蛋白-A 水平的降低与肝脏灌注不足相关，可预测心力衰竭患者的心脏结局。

• DOI: 10.1007/s00392-022-02023-0
• 发表时间: 2022
• 期刊: Clinical Research in Cardiology
• 影响因子: 5
• 作者: Tomita Yusuke;Misaka Tomofumi;Yoshihisa Akiomi;Ichijo Yasuhiro;Ishibashi Shinji;Matsuda Mitsuko;Yamadera Yukio;Ohara Himika;Sugawara Yukiko;Hotsuki Yu;Watanabe Koichiro;Anzai Fumiya;Sato Yu;Sato Takamasa;Oikawa Masayoshi;Kobayashi Atsushi;Takeishi Yasuchi
• 通讯作者: Takeishi Yasuchi

Hepatokine Selenoprotein P is associated with hypoperfusion and predicts adverse prognosis in heart failure patients

肝因子硒蛋白 P 与灌注不足相关，可预测心力衰竭患者的不良预后

• 发表时间: 2021
• 作者: Yasuhiro Ichijo;Tomofumi Misaka;Akiomi Yoshihisa;Yu Hotsuki;Koichiro Watanbe;Fumiya Anzai;Yu Sato;Yusuke Kimishima;Tetsuro Yokokawa;Masayoshi Oikawa;Atsushi Kobayashi;Yasuchika Takeishi
• 通讯作者: Yasuchika Takeishi