Mechanism of the regulation of osteoblast process formation by Runx2 through Tln2 regulation during osteoblast maturation

成骨细胞成熟过程中Runx2通过Tln2调节调控成骨细胞过程形成的机制

• 批准号: 19K18947
• 负责人: SAKANE Chiharu
• 金额: $ 2.75万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Early-Career Scientists
• 财政年份: 2019
• 资助国家: 日本
• 起止时间: 2019-04-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19K18947/
• 关键词: 骨芽細胞突起形成; Runx2; Tln2

项目成果

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts.

• DOI: 10.1371/journal.pgen.1009169
• 发表时间: 2020-11
• 期刊: PLoS genetics
• 影响因子: 4.5
• 作者: Qin X;Jiang Q;Nagano K;Moriishi T;Miyazaki T;Komori H;Ito K;Mark KV;Sakane C;Kaneko H;Komori T
• 通讯作者: Komori T

Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice

• DOI: 10.3390/ijms21082682
• 发表时间: 2020-04-01
• 期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
• 影响因子: 5.6
• 作者: Matsuura, Viviane K. S. Kawata;Yoshida, Carolina Andrea;Komori, Toshihisa
• 通讯作者: Komori, Toshihisa