German Ultrahigh Field Imaging (GUFI)

德国超高场成像 (GUFI)

• 批准号: 324669110
• 负责人: Professor Dr. Mark E. Ladd
• 金额: --
• 依托单位: Max-Planck-Institut für Kognitions- und Neurowissenschaften
• 依托单位国家: 德国
• 项目类别: Core Facilities
• 财政年份: 2017
• 资助国家: 德国
• 起止时间: 2016-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/324669110?language=en
• 关键词: German; Ultrahigh; Field; Imaging; GUFI

The German Ultrahigh Field Imaging (GUFI) network was founded at the end of 2013 with the aid of DFG funding provided by the call to establish Core Facilities including distributed national networks such as GUFI. Members of the GUFI network now include all eleven centers performing human ultra-high-field (UHF) magnetic resonance (MR) imaging at magnetic field strengths >= 7 Tesla in Germany. Several international partners are affiliated with the network as well. The overall goal of GUFI is to facilitate and harmonize the work of the German UHF MR sites and make this expensive and highly complex technology accessible to a larger number of researchers. The focus of the first funding period was to promote communication between the centers via a web-based portal as well as regular face-to-face meetings. The web portal also enables external users to identify the UHF MR facility best suited to their research question. A consensus guideline document has been formulated that gives basic recommendations regarding access procedures and rules for UHF MR research infrastructure. A consensus recommendation on how to determine whether subjects with passive implants can be safely examined at UHF MR has also been issued by the GUFI members. The network has established quality assurance (QA) procedures and a corresponding measurement phantom suitable for monitoring system performance and ensuring that each UHF MR system is working at peak performance. As an extension of this work, GUFI conducted and published a study examining measurement reproducibility across sites. This is the first study that paves the way for future multicenter research studies utilizing structural imaging at UHF. In the upcoming funding period, a main focus will be continuation of the networking and communication activities. We will also further pursue our efforts to establish consensus safety procedures, including common and mutually recognized staff and user training based on an online course, establishment of a database of specific implants that can be safely accepted for imaging, and consensus regarding testing and evaluation of self-built radiofrequency coils. We also aim to refine our QA activities by developing QA protocols suitable for regions outside the brain and by establishing tools for automated, quantitative evaluation of data collected during QA procedures. First multicenter trials will be planned and initiated. The German UHF MR community was the first national UHF MR community to coordinate their efforts in a network such as GUFI, and the high visibility of this project is demonstrated by the active involvement of international UHF MR sites and the establishment of a UK UHF MR network based on a similar concept, with which GUFI closely cooperates.

德国超高场成像(GUFI)网络是在DFG的资助下于2013年底建立的，该呼吁旨在建立核心设施，包括GUFI等分布式国家网络。GUFI网络的成员现在包括在德国以磁场强度<gt；=7特斯拉进行人体超高场(UHF)磁共振(MR)成像的所有11个中心。几个国际合作伙伴也加入了该网络。GUFI的总体目标是促进和协调德国超高频磁共振站点的工作，并使更多的研究人员能够使用这项昂贵而高度复杂的技术。第一个资助期的重点是通过基于网络的门户以及定期面对面会议促进中心之间的交流。该门户网站还使外部用户能够确定最适合其研究问题的超高频磁共振设备。已经制定了一份协商一致的指导文件，就超高频磁共振研究基础设施的准入程序和规则提出了基本建议。GUFI成员还发布了一项共识建议，即如何确定被动植入物的受试者是否可以在UHF MR中安全地进行检查。该网络建立了质量保证(QA)程序和相应的测量模型，适用于监控系统性能并确保每个UHF MR系统以最佳性能工作。作为这项工作的延伸，GUFI进行并发表了一项研究，检查了跨地点测量的重复性。这是第一项为未来利用超高频结构成像进行多中心研究铺平道路的研究。在即将到来的供资期间，主要重点将是继续开展网络和通信活动。我们还将进一步努力建立共识安全程序，包括基于在线课程的共同和相互认可的工作人员和用户培训，建立可安全接受成像的特定植入物数据库，以及就自建射频线圈的测试和评估达成共识。我们还旨在通过开发适用于大脑以外区域的QA协议，并通过建立工具来对QA过程中收集的数据进行自动、定量的评估，来完善我们的QA活动。将计划和启动第一批多中心试验。德国超高频磁共振社区是第一个在GUFI这样的网络中协调其努力的国家UHF MR社区，该项目的高度可见性体现在国际UHF MR站点的积极参与以及基于类似概念的英国UHF MR网络的建立，GUFI与该网络密切合作。