GERMANET. the nationwide GERman MAss cytometry NETwork: project-specific supervision, exchange of expertise, technology transfer, data analysis
日耳曼网。
基本信息
- 批准号:324736178
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:德国
- 项目类别:Core Facilities
- 财政年份:2017
- 资助国家:德国
- 起止时间:2016-12-31 至 2021-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The recently developed mass cytometry (CyTOF technology) captures the complexity of cellular systems at unprecedented depth, promising significant contributions in biomedical research and diagnostics. The German Rheumatism Research Center Berlin (DRFZ) initiates the foundation of a nationwide mass cytometry network, GERMANET (GERman MAss cytometry NETwork), that bundles expertise of all German mass cytometry centers, at the DRFZ, the Berlin-Brandenburg Center for Regenerative Therapies (BCRT, Charité Berlin), the Center for Regenerative Therapies of the TU Dresden (CRTD), and the University Clinics Ulm. The complexity of mass cytometry projects represents significant hurdles and risks for individual researchers, which will be minimized by interconnecting and joining forces of German mass cytometry centers along a divide-and-conquer strategy. Aims of this network are to i) boost communication between new and experienced users, technology developers, and data analysis experts, to benefit individual researchers projects, ii) the exploitation of synergies in panel design and technology developoment arising from the centers complementary research scope, iii) quality assurance of mass cytometric analyses and data, and their reproducibility, and iv) facilitating bioinformatic analyses. This will be achieved by i) intense project supervision in the planning, execution and analysis phase, joint regular workshops and seminars, the installation of the researcher exchange programme and mutual technology transfer, ii) the introduction of modular panels and the development of new technologies, iii) establishing joint quality standards and their integration into routines, and their validation in ring-trials, and iv) installing the Bioinformatics Contact Office. Thus, GERMANET facilitates the international competitiveness of German mass cytometry.
最近开发的质谱仪(CyTOF技术)以前所未有的深度捕获了细胞系统的复杂性,为生物医学研究和诊断做出了重大贡献。德国风湿病研究中心柏林(DRFZ)发起了一个全国性的质谱细胞计数网络GERMANET(GERman MASS cytometry NETwork)的建立,该网络汇集了德国所有质谱细胞计数中心的专业知识,包括DRFZ、柏林-勃兰登堡再生治疗中心(BCRT,Charité柏林)、德累斯顿工业大学再生治疗中心(CRTD)和乌尔姆大学诊所。大规模细胞计数项目的复杂性对单个研究人员来说是重大的障碍和风险,通过德国大规模细胞计数中心的相互联系和联合,沿着分而治之的战略,这将被最小化。该网络的目的是i)促进新用户和经验丰富的用户,技术开发人员和数据分析专家之间的沟通,以使个人研究人员项目受益,ii)利用中心互补研究范围产生的面板设计和技术开发的协同作用,iii)质量保证质谱分析和数据及其再现性,以及iv)促进生物信息学分析。这将通过以下方式实现:一)在规划、执行和分析阶段加强项目监督,联合定期讲习班和研讨会,实施研究人员交流方案和相互技术转让,二)采用模块化面板和开发新技术,三)建立联合质量标准,将其纳入常规,并在环试中进行验证,和iv)建立生物信息学联络办公室。因此,GERMANET促进了德国质谱细胞仪的国际竞争力。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Dr. Henrik Mei其他文献
Dr. Henrik Mei的其他文献
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{{ truncateString('Dr. Henrik Mei', 18)}}的其他基金
Leukocytes as biosensors for clinical parameters, the effects of novel therapeutics and prediction of disease course in patients with SLE
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-- - 项目类别:
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