Understanding, prediction and control of polymorphism in pharmaceuticals.

药物多态性的理解、预测和控制。

• 批准号: DP0770665
• 负责人: Prof Thomas Welberry
• 金额: $ 17.63万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0770665
• 关键词: Understanding; prediction; control; polymorphism; pharmaceuticals.

The proposed research will lead, through a better understanding of polymorphism, to more efficient production of pharmaceuticals and will enhance the establishment and protection of patents. The work will have flow-on in other areas such as the manufacture of pigments, dyes and explosives. The project uses methodology for the elucidation of local structure and function at the atomic to nanoscale level in which Australia is a world leader. The project will further enhance our standing in this field and will provide excellent research training opportunities in areas particularly pertinent to future exploitation of the Australian Synchrotron and the new Research Reactor OPAL, which open in 2007.

拟议的研究将通过更好地了解多态性，导致更有效地生产药品，并将加强专利的建立和保护。这项工作将在颜料、染料和炸药的制造等其他领域得到推广。该项目使用方法学来阐明原子到纳米级的局部结构和功能，澳大利亚在这方面处于世界领先地位。该项目将进一步提高我们在该领域的地位，并将在与澳大利亚同步加速器和新的研究反应堆OPAL的未来开发有关的领域提供优秀的研究培训机会，该反应堆将于2007年投入使用。