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Mortality and associated characteristics of an adult population with mental disorders

患有精神障碍的成年人的死亡率和相关特征

基本信息

批准号：
329858602
负责人：
Professor Dr. Ulrich John
金额：
--
依托单位：
Klinik für Psychiatrie und Psychotherapie
依托单位国家：
德国
项目类别：
Research Grants
财政年份：
2017
资助国家：
德国
起止时间：
2016-12-31 至 2021-12-31
项目状态：
已结题

来源：
https://gepris.dfg.de/gepris/projekt/329858602?language=en
关键词：
Mortality associated characteristics adult population

项目摘要

Evidence shows that mentally ill persons among the general population die earlier than those without mental disease. Limitations of research include that epidemiological studies did not use modern standardized psychiatric diagnostic systems, and that detailed information about health risk behaviors are missing, particularly about tobacco smoking and alcohol consumption. Findings according to somatoform disorders are missing, and we lack knowledge about utilization of psychiatric care and other medical care with respect to mortality risks. Therefore, work that we did before includes one baseline survey of a random sample of 4,075 adults at age 18 to 64 in the general population of a German region in the year 1996. We published a second study about the mortality risks of those who had been diagnosed at baseline as ever having fulfilled the criteria of alcohol dependence in lifetime before compared to those without such a diagnosis. We concluded from this second study that the planned project will be feasible. Its aims include, first, to analyze mortality rates per specific diagnosis among three subgroups of the sample - individuals with substance use disorders, individuals with affective disorders, and individuals with somatoform disorders - 20 years after baseline. The second aim is to compare those those who are still alive with those have been deceased including time to death according to single characteristics of tobacco smoking and alcohol risk drinking. Third, we will analyze whether the same lifetime exposure to tobacco smoke with or without nicotine dependence is related to different mortality risks. Fourth, mortality risks among those with somatoform disorders are to be analyzed compared to those without. Fifth, utilization of psychiatric and further medical care will be analyzed among patients with single disorders. The work program includes the collection of vital status data, i. e. whether a single person has been deceased, and if, at which date. Causes of death are to be analyzed from death certificates. Work will particularly include address searches and publication of the data according to each single study aim.

有证据表明，一般人口中的精神病患者比没有精神病的人早死。研究的局限性包括流行病学研究没有使用现代标准化的精神病诊断系统，以及缺乏有关健康风险行为的详细信息，特别是关于吸烟和饮酒的信息。根据躯体形式障碍的研究结果缺失，我们缺乏关于利用精神科护理和其他医疗护理与死亡风险相关的知识。因此，我们之前所做的工作包括1996年对德国一个地区一般人口中年龄在18岁至64岁之间的4，075名成年人进行随机抽样的基线调查。我们发表了第二项研究，研究了那些在基线时被诊断为酒精依赖的人与那些没有被诊断为酒精依赖的人相比的死亡风险。我们从第二项研究中得出结论，计划的项目是可行的。其目的包括，首先，分析基线后20年样本中三个亚组（物质使用障碍个体、情感障碍个体和躯体形式障碍个体）每种特定诊断的死亡率。第二个目的是比较那些仍然活着的人与那些已经死亡的人，包括死亡时间，根据吸烟和饮酒风险的单一特征。第三，我们将分析是否有尼古丁依赖或无尼古丁依赖的相同终生暴露于烟草烟雾与不同的死亡风险有关。第四，将与无躯体形式障碍的人相比，分析患有躯体形式障碍的人的死亡风险。第五，将分析单一疾病患者对精神病和进一步医疗护理的利用。工作方案包括收集生命状态数据，即：e.一个人是否已经死亡，如果，在哪一天。死亡原因将根据死亡证明进行分析。工作将特别包括地址搜索和根据每项研究目标公布数据。