Control of the Enantiomeric Self-Resolution Process

对映体自行拆分过程的控制

• 批准号: DP0771614
• 负责人: Em/Prof Roger Bishop
• 金额: $ 16.66万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0771614
• 关键词: Control; Enantiomeric; Self; Resolution; Process

The availability of enantiopure molecules is crucial in chemistry and medicine. Enantiomeric self-resolution on crystallisation provides pure left- and right-handed molecules from 1:1 mixtures of the two. It is the simplest and cheapest means of obtaining enantiopure molecules, but its occurrence in any given case cannot normally be predicted. The understanding and control of the self-resolution process gained through this project will represent a major breakthrough in organic and pharmaceutical chemistry. This technological advance will make pure handed molecules available readily and cheaply, thereby allowing chemical, pharmaceutical and biological developments to be made by Australian industry.

对映体分子的可用性在化学和医学上是至关重要的。对映体在结晶时的自拆分从两者的1：1混合物中提供了纯的左旋和右旋分子。这是获得对映体分子的最简单和最便宜的方法，但在任何给定的情况下，它的出现通常不是 预测到了。通过该项目获得的对自拆分过程的理解和控制将是有机化学和药物化学的重大突破。这一技术进步将使纯手分子容易且廉价地获得，从而使澳大利亚工业能够进行化学、制药和生物开发。