Reg growth factors in gastric regeneration and disease

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This project will obtain a more detailed knowledge of the role that growth factors play in helping the lining of the stomach repair itself after damage caused by disease. Growth factors may also play a role in causing stomach cancer. To do this we will examine the expression of growth factors in number of stomach diseases and cancer and assay the ability of growth factors to promote the growth of stomach cells. This work is that it will contribute to our knowledge of how cell growth in the stomach is controlled under normal circumstances and in the very common pathological conditions of tissue damage, inflammation and cancer. It may also help us understand how inflammation can in some circumstances lead to cancer.