Priming of plant defence against pathogens and herbivores by DNA damage signalling (B05)

通过 DNA 损伤信号启动植物防御病原体和食草动物 (B05)

• 批准号: 358447592
• 金额: --
• 依托单位: Abteilung Biochemie pflanzlicher Interaktionen
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2017
• 资助国家: 德国
• 起止时间: 2016-12-31 至 2019-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/358447592?language=en
• 关键词: Priming; plant; defence; against; pathogens

Phytopathogen infections lead to plant DNA damage; several components of DNA damage responses are required for activation of plant innate immunity. Application of bleomycin, a DNA double strand break-inducing glycopeptide, can prime the expression of plant defence genes against subsequent pathogen stress over several days. Project B5 will study molecular mechanisms underlying this priming effect. Insect oviposition on leaves leads to transcriptome changes that resemble those upon pathogen attack. Therefore, we will also assess if oviposition elicits DNA lesions and whether molecular responses to DNA damage contribute to oviposition-mediated anti-herbivore priming.

植物病原体侵染导致植物DNA损伤；DNA损伤反应的几个组成部分是激活植物天然免疫所必需的。应用博莱霉素，一种DNA双链断裂诱导糖肽，可以启动植物防御基因的表达，以抵御随后几天的病原菌胁迫。B5项目将研究这种启动效应背后的分子机制。昆虫在叶片上产卵导致转录组的变化，类似于病原菌攻击时的变化。因此，我们还将评估产卵是否会引起DNA损伤，以及对DNA损伤的分子反应是否有助于产卵介导的抗草食动物启动。