Elucidation of the molecular mechanism underlying TTR monomer unfolding and aggregate formation and its application to therapeutic approaches for FAP
Elucidation of the molecular mechanism underlying TTR monomer unfolding and aggregate formation and its application to therapeutic approaches for FAP
批准号:
18K06659
负责人:
Sato Takashi
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2018
资助国家:
日本
项目状态:
已结题
起止时间:
2018-04-01 至 2021-03-31
中文摘要
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期刊论文(12)
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トランスサイレチンの品質管理における小胞体分子シャペロンBiPの基質認識機構の解析
内质网分子伴侣BiP在转甲状腺素蛋白质量控制中的底物识别机制分析
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[Yuriko Wakita, Takashi Sato, Keisuke Chosa, Mary Ann Suico, Ryoko Sasaki, Shingo Kawano, Nami Hashimoto, Yuriko Teranishi, Yoshiki Imai, Hiroshi Morioka, Tsuyoshi Shuto, Hirofumi Kai, 小野祐一朗,稲田祐貴,小橋川敬博,首藤剛,甲斐広文,森岡弘志,佐藤卓史, Yuki Inada,Takashi Sato,Kentaro Noi,Ryoko Sasaki,Yuichiro Ono,Yoshihiro Kobashigawa,Tsuyoshi Shuto,Hirofumi Kai,Hiroshi Morioka, 稲田祐貴,小野祐一朗,佐々木亮子,小橋川敬博,首藤 剛,甲斐広文,森岡弘志,佐藤卓史, 稲田祐貴,佐藤卓史,小野祐一朗,小橋川敬博,甲斐広文,森岡弘志, 稲田祐貴,小野祐一朗,佐々木亮子,小橋川敬博,首藤剛,甲斐広文,森岡弘志,佐藤卓史, 稲田祐貴,小野祐一朗,小橋川敬博,首藤剛,甲斐広文,森岡弘志,佐藤卓史, 稲田祐貴,佐藤卓史,河野慎吾,小橋川敬博,甲斐広文,森岡弘志, 稲田祐貴,佐藤卓史,河野慎吾,小橋川敬博,甲斐広文,森岡弘志]
通讯作者:
稲田祐貴,佐藤卓史,河野慎吾,小橋川敬博,甲斐広文,森岡弘志
トランスサイレチンのアミロイド形成過程の新規中間体S-S dimerの機能解析
转甲状腺素蛋白淀粉样蛋白形成过程中的新型中间体 S-S 二聚体的功能分析
DOI:
--
发表时间:
2020
期刊:
影响因子:
--
作者:
[Yuriko Wakita, Takashi Sato, Keisuke Chosa, Mary Ann Suico, Ryoko Sasaki, Shingo Kawano, Nami Hashimoto, Yuriko Teranishi, Yoshiki Imai, Hiroshi Morioka, Tsuyoshi Shuto, Hirofumi Kai, 小野祐一朗,稲田祐貴,小橋川敬博,首藤剛,甲斐広文,森岡弘志,佐藤卓史, Yuki Inada,Takashi Sato,Kentaro Noi,Ryoko Sasaki,Yuichiro Ono,Yoshihiro Kobashigawa,Tsuyoshi Shuto,Hirofumi Kai,Hiroshi Morioka, 稲田祐貴,小野祐一朗,佐々木亮子,小橋川敬博,首藤 剛,甲斐広文,森岡弘志,佐藤卓史]
通讯作者:
稲田祐貴,小野祐一朗,佐々木亮子,小橋川敬博,首藤 剛,甲斐広文,森岡弘志,佐藤卓史
アミロイド形成過程におけるトランスサイレチンの新規中間体構造の機能解析
淀粉样蛋白形成过程中转甲状腺素蛋白新型中间结构的功能分析
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[Yuriko Wakita, Takashi Sato, Keisuke Chosa, Mary Ann Suico, Ryoko Sasaki, Shingo Kawano, Nami Hashimoto, Yuriko Teranishi, Yoshiki Imai, Hiroshi Morioka, Tsuyoshi Shuto, Hirofumi Kai, 小野祐一朗,稲田祐貴,小橋川敬博,首藤剛,甲斐広文,森岡弘志,佐藤卓史, Yuki Inada,Takashi Sato,Kentaro Noi,Ryoko Sasaki,Yuichiro Ono,Yoshihiro Kobashigawa,Tsuyoshi Shuto,Hirofumi Kai,Hiroshi Morioka, 稲田祐貴,小野祐一朗,佐々木亮子,小橋川敬博,首藤 剛,甲斐広文,森岡弘志,佐藤卓史, 稲田祐貴,佐藤卓史,小野祐一朗,小橋川敬博,甲斐広文,森岡弘志, 稲田祐貴,小野祐一朗,佐々木亮子,小橋川敬博,首藤剛,甲斐広文,森岡弘志,佐藤卓史]
通讯作者:
稲田祐貴,小野祐一朗,佐々木亮子,小橋川敬博,首藤剛,甲斐広文,森岡弘志,佐藤卓史
Unfolding-dependent disulfide-linked dimer formation leads to the transthyretin amyloid assembly pathway toward the production of cytotoxic aggregate
解折叠依赖性二硫键连接二聚体形成导致转甲状腺素蛋白淀粉样蛋白组装途径产生细胞毒性聚集体
DOI:
--
发表时间:
2020
期刊:
影响因子:
--
作者:
[Yuriko Wakita, Takashi Sato, Keisuke Chosa, Mary Ann Suico, Ryoko Sasaki, Shingo Kawano, Nami Hashimoto, Yuriko Teranishi, Yoshiki Imai, Hiroshi Morioka, Tsuyoshi Shuto, Hirofumi Kai, 小野祐一朗,稲田祐貴,小橋川敬博,首藤剛,甲斐広文,森岡弘志,佐藤卓史, Yuki Inada,Takashi Sato,Kentaro Noi,Ryoko Sasaki,Yuichiro Ono,Yoshihiro Kobashigawa,Tsuyoshi Shuto,Hirofumi Kai,Hiroshi Morioka]
通讯作者:
Yuki Inada,Takashi Sato,Kentaro Noi,Ryoko Sasaki,Yuichiro Ono,Yoshihiro Kobashigawa,Tsuyoshi Shuto,Hirofumi Kai,Hiroshi Morioka
DOI:
10.1038/s41598-020-68681-0
发表时间:
2020-07-20
期刊:
SCIENTIFIC REPORTS
影响因子:
4.6
作者:
[Urabe, Gen, Sato, Takashi, Katsuki, Sunao]
通讯作者:
Katsuki, Sunao
共 11 条
Exploration of differentiation programs in lung cancers using epigenomic profiling
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批准号:20K17192
-
项目类别:Grant-in-Aid for Early-Career Scientists
-
资助金额:$2.75万
-
财政年份:2020
-
负责人:Sato Takashi
-
依托单位:
Clonable PUF: Physical Unclonable Function with Limited Replication
-
批准号:20K21793
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$3.99万
-
财政年份:2020
-
负责人:Sato Takashi
-
依托单位:
Elucidation of the new developmental mechanism of pancreatic endocrine tissue by cell linage
-
批准号:19K06435
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2019
-
负责人:Sato Takashi
-
依托单位:
Facial nerve regeneration with using a nanofiber sheet incorporating methylcobalamin,
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批准号:18K09346
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2018
-
负责人:Sato Takashi
-
依托单位:
Development of innovative delivery systems of biologics to the lung
-
批准号:18K19935
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$3.99万
-
财政年份:2018
-
负责人:Sato Takashi
-
依托单位:
Development of Time-Varying Chip-ID Based on Transistor Models Considering Transient Degradation
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批准号:17H01713
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.9万
-
财政年份:2017
-
负责人:Sato Takashi
-
依托单位:
Unconscious, non-contact, and continuous bital sensing
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批准号:15K12700
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2015
-
负责人:Sato Takashi
-
依托单位:
Research on Ishida Kazuo's Thought on Education and Review of Education of Writing about Life in Ena region
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批准号:26381034
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
-
财政年份:2014
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负责人:Sato Takashi
-
依托单位:
Development of an education program for promoting higher-level engineers by considering their diverse study history
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批准号:26301042
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.65万
-
财政年份:2014
-
负责人:Sato Takashi
-
依托单位:
Pharmaceutical studies for the elucidation and prevention of molecule-targeting therapeutic agents-induced acne-like rash in cancer patients
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批准号:26460633
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.16万
-
财政年份:2014
-
负责人:Sato Takashi
-
依托单位:
Reliability design for lifetime prediction, failure prevention, and degradation recovery of integrated circuits
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批准号:26280014
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.98万
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财政年份:2014
-
负责人:Sato Takashi
-
依托单位:
Analyses of candidate genes with multi-step DNA methylation alterations in lung cancer
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批准号:26870569
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2014
-
负责人:Sato Takashi
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依托单位:
Elucidation of communication emergence mechanism based on action time series in reinforcement learning agents.
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批准号:25871049
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.91万
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财政年份:2013
-
负责人:Sato Takashi
-
依托单位:
Fast physical random number generation making use of frequency noise characteristics of a vertical cavity surface emitting lasers
-
批准号:25390093
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2013
-
负责人:Sato Takashi
-
依托单位:
海外基金