Innovative approach to anti-MDA5 antibody-positive dermatomyositis; Development of animal models and understanding of pathogenesis
Innovative approach to anti-MDA5 antibody-positive dermatomyositis; Development of animal models and understanding of pathogenesis
批准号:
18K19532
负责人:
Sato Shinichi
金额:
$3.99万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
财政年份:
2018
资助国家:
日本
项目状态:
已结题
起止时间:
2018-06-29 至 2020-03-31
中文摘要
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英文摘要
期刊论文(15)
专著(0)
科研奖励(0)
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Direct Interaction between Autoreactive B Cells and Endothelial Colony Forming Cells Induces Cytokine Production from B cells through B Cell Receptor and IL-6-JAK2-STAT3 Signaling Pathway, Suppressing Proliferation of Endothelial Colony Forming Cells in S
自身反应性 B 细胞与内皮集落形成细胞之间的直接相互作用通过 B 细胞受体和 IL-6-JAK2-STAT3 信号通路诱导 B 细胞产生细胞因子,从而抑制 S 中内皮集落形成细胞的增殖
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[Fukasawa T, Yoshizaki A, Ebata S, Nakamura K, Asano Y, Kazoe Y, Mawatari K, Kitamori T, Sato S]
通讯作者:
Sato S
Serum levels of human β-defensin 2: possible association with fibrosis and vasculopathy in patients with systemic sclerosis.
人β-防御素2的血清水平:可能与系统性硬化症患者的纤维化和血管病变相关。
DOI:
10.1111/jdv.15546
发表时间:
2019
期刊:
J Eur Acad Dermatol Venereol.
影响因子:
--
作者:
[Kuzumi A, Yoshizaki A, Fukasawa T, Ebata S, Miura S, Yoshizaki A, Sumida H, Asano Y, Sato S.]
通讯作者:
Sato S.
DOI:
10.1016/j.jdermsci.2018.09.007
发表时间:
2019-01
期刊:
Journal of dermatological science
影响因子:
4.6
作者:
[T. Yamashita;Y. Asano;R. Saigusa;Takashi Taniguchi;Kouki Nakamura;S. Miura;T. Toyama;Takehiro Takahashi-Takeh]
通讯作者:
T. Yamashita;Y. Asano;R. Saigusa;Takashi Taniguchi;Kouki Nakamura;S. Miura;T. Toyama;Takehiro Takahashi-Takeh
全身性強皮症における血管障害に対するtopoisomerase I特異的B細胞の役割
拓扑异构酶 I 特异性 B 细胞对系统性硬皮病血管损伤的作用
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[深澤毅倫, 吉崎歩, 江畑慧, 久住藍, 平川麻衣子, 吉崎麻子, 浅野善英, 嘉副裕, 馬渡和真, 北森武彦, 佐藤伸一]
通讯作者:
佐藤伸一
Tissue microenvironment maintains tissue-resident B cells during B cell depletion therapy in systemic sclerosis
系统性硬化症 B 细胞耗竭治疗期间,组织微环境维持组织驻留 B 细胞
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[Ayumi Yoshizaki, Ai Kuzumi, Takemichi Fukasawa, Satoshi Ebata, Shinichi Sato]
通讯作者:
Shinichi Sato
共 10 条
Identification of a true extracellular autoantigen that cross-reacts with autoantibodies in systemic sclerosis.
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批准号:21K19472
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
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财政年份:2021
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负责人:Sato Shinichi
-
依托单位:
Target identification of bioactive molecules based on detection of protein denaturation state
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批准号:19H02848
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2019
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负责人:Sato Shinichi
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依托单位:
Research on the Use of 360-degree Movies to Facilitate International Collaborative Learning
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批准号:18K02841
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2018
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负责人:Sato Shinichi
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依托单位:
Comprehensive analysis of autoantigen-reactive B cell in systemic sclerosis and identification of therapeutic targets
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批准号:17H04239
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.73万
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财政年份:2017
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负责人:Sato Shinichi
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依托单位:
Search for effective artificial amniotic fluid purification method
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批准号:17K16295
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.58万
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财政年份:2017
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负责人:Sato Shinichi
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依托单位:
The development of new therapies targeting the three cardinal pathological processes of systemic sclerosis
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批准号:16K15511
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.16万
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财政年份:2016
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负责人:Sato Shinichi
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依托单位:
Site Specific Antibody Modification Using Catalyst-Functionalized Affinity Beads
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批准号:15K12742
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.25万
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财政年份:2015
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负责人:Sato Shinichi
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依托单位:
The generation of a new animal model of systemic sclerosis by focusing on environmental factors
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批准号:26670520
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2014
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负责人:Sato Shinichi
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依托单位:
The establishment of animal models of systemic sclerosis based on Fli1 deficiency
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批准号:25293242
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.81万
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财政年份:2013
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负责人:Sato Shinichi
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依托单位:
海外基金