Comprehensive analysis of autoantigen-reactive B cell in systemic sclerosis and identification of therapeutic targets
Comprehensive analysis of autoantigen-reactive B cell in systemic sclerosis and identification of therapeutic targets
批准号:
17H04239
负责人:
Sato Shinichi
金额:
$10.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2017
资助国家:
日本
项目状态:
已结题
起止时间:
2017-04-01 至 2020-03-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
The novel micro-fluidic system reveals the pathogenic roles of vascular endothelium-specific B cells in cutaneous arteritis
新型微流体系统揭示了血管内皮特异性 B 细胞在皮动脉炎中的致病作用
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Ayumi Yoshizaki, Kouki Nakamura, Satoshi Ebata, Takemichi Fukasawa, Yoshihide Asano, Yutaka Kazoe, Kazuma Mawatari, Takehiko Kitamori, Shinichi Sato]
通讯作者:
Shinichi Sato
Rapid alteration of serum interleukin-6 levels may predict the reactivity of i.v. cyclophosphamide pulse therapy in systemic sclerosis-associated interstitial lung disease.
血清白细胞介素 6 水平的快速变化可以预测静脉注射的反应性。
DOI:
10.1111/1346-8138.14580
发表时间:
2018
期刊:
J Dermatol.
影响因子:
--
作者:
[Numajiri H, Yoshizaki A, Fukasawa T, Ebata S, Nakamura K, Yamashita T, Saigusa R, Miura S, Hirabayashi M, Yoshizaki A, Sumida H, Asano Y, Kazoe Y, Mawatari K, Kitamori T, Sato S.]
通讯作者:
Sato S.
Microenvironment in systemic sclerosis provides a protective niche for tissue-resident B cells during B cell depletion therapy with anti-CD20 antibody
在使用抗 CD20 抗体进行 B 细胞耗竭治疗期间,系统性硬化症的微环境为组织驻留 B 细胞提供了保护性生态位
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[Ai Kuzumi, Ayumi Yoshizaki, Takemichi Fukasawa, Satoshi Ebata, Yoshihide Asano, Shinichi Sato]
通讯作者:
Shinichi Sato
Elevated Serum Interleukin-34 Levels Are Correlated with Interstitial Lung isease in Systemic Sclerosis
血清白细胞介素 34 水平升高与系统性硬化症中的间质性肺疾病相关
DOI:
--
发表时间:
2018
期刊:
影响因子:
--
作者:
[Suga H, Kuzumi A, Asano Y, Yoshizaki A, Sato S]
通讯作者:
Sato S
Fli1 Deficiency Induces CXCL6 Expression in Dermal Fibroblasts and Endothelial Cells, Contributing to the Development of Fibrosis and Vasculopathy in Systemic Sclerosis.
Fli1 缺陷会诱导真皮成纤维细胞和内皮细胞表达 CXCL6,从而导致系统性硬化症中纤维化和血管病变的发生。
DOI:
10.3899/jrheum.161092
发表时间:
2017
期刊:
J Rheumatol.
影响因子:
--
作者:
[Taniguchi T, Asano Y, Nakamura K, Yamashita T, Saigusa R, Ichimura Y, Takahashi T, Toyama T, Yoshizaki A, Sato S.]
通讯作者:
Sato S.
共 23 条
Identification of a true extracellular autoantigen that cross-reacts with autoantibodies in systemic sclerosis.
-
批准号:21K19472
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.16万
-
财政年份:2021
-
负责人:Sato Shinichi
-
依托单位:
Target identification of bioactive molecules based on detection of protein denaturation state
-
批准号:19H02848
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.32万
-
财政年份:2019
-
负责人:Sato Shinichi
-
依托单位:
Innovative approach to anti-MDA5 antibody-positive dermatomyositis; Development of animal models and understanding of pathogenesis
-
批准号:18K19532
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$3.99万
-
财政年份:2018
-
负责人:Sato Shinichi
-
依托单位:
Research on the Use of 360-degree Movies to Facilitate International Collaborative Learning
-
批准号:18K02841
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2018
-
负责人:Sato Shinichi
-
依托单位:
Search for effective artificial amniotic fluid purification method
-
批准号:17K16295
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.58万
-
财政年份:2017
-
负责人:Sato Shinichi
-
依托单位:
The development of new therapies targeting the three cardinal pathological processes of systemic sclerosis
-
批准号:16K15511
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.16万
-
财政年份:2016
-
负责人:Sato Shinichi
-
依托单位:
Site Specific Antibody Modification Using Catalyst-Functionalized Affinity Beads
-
批准号:15K12742
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.25万
-
财政年份:2015
-
负责人:Sato Shinichi
-
依托单位:
The generation of a new animal model of systemic sclerosis by focusing on environmental factors
-
批准号:26670520
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2014
-
负责人:Sato Shinichi
-
依托单位:
The establishment of animal models of systemic sclerosis based on Fli1 deficiency
-
批准号:25293242
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.81万
-
财政年份:2013
-
负责人:Sato Shinichi
-
依托单位:
海外基金