Regulation of axonal arbor and synaptic dynamics via interactions between the extrinsic apoptotic pathway and membrane trafficking

通过外在凋亡途径和膜运输之间的相互作用调节轴突乔木和突触动力学

• 批准号: 19K21215
• 负责人: Campbell Douglas
• 金额: $ 1.91万
• 依托单位: Kyoto University (2020-2021)Waseda University (2018-2019)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Research Activity Start-up
• 财政年份: 2018
• 资助国家: 日本
• 起止时间: 2018-08-24 至 2022-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19K21215/
• 关键词: Neuron; Synapse; Axon; Membrane trafficking; Branch; Caspase; Endosome; Visual System; Membrane; Trafficking; Apoptosis; Endocytosis; Remodelling; Arbor; Zebrafish; Neuroscience; Neuronal remodeling; Cell Biology; Bioimaging; Intracellu

项目成果

A catalytic activity-independent role for the extrinsic apoptotic pathway interacting with early endosomes to restrict axonal arbor growth and synaptogenesis in vivo

外在细胞凋亡途径与早期内体相互作用以限制体内轴突乔木生长和突触发生的催化活性独立作用

• 发表时间: 2021
• 作者: 藤原勝夫;清田直恵;外山寛;Ilya N. Kotov and Douglas S. Campbell
• 通讯作者: Ilya N. Kotov and Douglas S. Campbell

Connecting The Eye to The Brain: Interactions Between the Apoptotic Pathway and Membrane Trafficking

连接眼睛与大脑：凋亡途径与膜运输之间的相互作用

• 发表时间: 2020
• 作者: 藤川理沙子;山田純;神野尚三;Ilya N. Kotov and Douglas S. Campbell;Douglas S. Campbell
• 通讯作者: Douglas S. Campbell

Connecting The Eye To The Brain: A Model System For Studying Cell Biology and Neuronal Connectivity

连接眼睛与大脑：研究细胞生物学和神经元连接的模型系统

• 发表时间: 2019
• 作者: 藤川理沙子;山田純;神野尚三;Ilya N. Kotov and Douglas S. Campbell;Douglas S. Campbell;Ilya N. Kotov and Douglas S. Campbell;Douglas Campbell
• 通讯作者: Douglas Campbell