Inhibitory spillover and inhibitory control of eating behavior

虽然心理和药物干预与超重个体的体重显著减轻有关，但大多数个体在这些干预后仍然超重。在这种情况下，经常提到的问题之一是高度可口的食物无处不在。 同时，并不是所有的个体都同样容易受到诱惑性食物的影响，最近的证据表明，与饮食相关的抑制缺陷与超重的维持有关。最近的研究还表明，在一个领域执行自我控制可能会导致另一个领域的抑制控制的同时增加。更多的临床相关性，这种随后的抑制控制的增加不能完全通过内源性线索来实现，但也可以通过抑制控制的外源性提醒来实现。本项目的目的是测试（1）伊势是否可以发生在病理性进食行为的领域，（2）伊势在食物相关反应抑制的测量中是明显的，（3）外源性信号的伊势促进超重和肥胖个体的体重减轻。这些研究问题将在一系列实验中在不同的体重样本中得到解决。我们假设（1）与正常体重个体相比，在食物无关的领域中施加抑制控制将减少超重个体在味觉测试中的食物摄入量，（2）抑制控制溢出到超重/肥胖个体通常缺乏的反应抑制方面，以及（3）以食物刺激为条件的伊势将促进四周内的体重减轻。

Although psychological and pharmacological interventions are associated with significant weight loss in overweight individuals, most individuals remain overweight after such interventions. One of the issues frequently addressed in this context is the omnipresence of highly palatable food. At the same time, not all individuals are equally susceptible to the high availability of tempting food and recent evidence suggests that eating-related inhibitory deficits are related to the maintenance of overweight.Recent research has also demonstrated that the execution of self-control in one domain may lead to a concurrent increase of inhibitory control in another domain. Of more clinical relevance, this subsequent increase in inhibitory control cannot be achieved exclusively by endogenous cues, but also exogenous reminders of inhibitory control.The aim of the present project is to test whether (1) ISE can occur in the domain of pathological eating behavior, (2) ISE are evident in measures of food-related response inhibition, and (3) ISE by exogenous cues facilitate weight reduction in overweight and obese individuals.These research questions will be addressed in different samples of weight in a series of experiments. We assume that (1) exertion of inhibitory control in a food-unrelated domain will decrease food intake in a taste test in overweight compared to normal weight individuals, (2) inhibitory control spills over to facets of response inhibition typically deficient in overweight/obese individuals, and (3) ISE conditioned to food stimuli will facilitate weight loss over a four-week period.