Inhomogeneous tissue conductivity influence on the forward and inverse electroencephalogram problems in realistic head models

不均匀组织电导率对现实头部模型中正向和反向脑电图问题的影响

• 批准号: DP0665216
• 负责人: Prof Peng (Paul) Wen
• 金额: $ 9.3万
• 依托单位: University of Southern Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-27 至 2010-11-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0665216
• 关键词: Inhomogeneous; tissue; conductivity; influence; forward

The brain dysfunction indicators have been extremely difficult to obtain, largely because many disorders of higher brain function reflect abnormalities of brain function rather than apparent brain structure. The neuronal generator localization and identification in this project will provide complementary information about source and timing of neural activities sub-serving higher brain function and form sequences of spatial-temporal brain activity image. That will enable the information from MRI, which has a good spatial but poor temporal resolution, and the information from EEG, which has a high temporal resolution on the scalp, to be combined to provide clinical psychologists and brain researchers a more efficient diagnostic tool.

脑功能障碍指标非常难以获得，主要是因为许多高级脑功能障碍反映的是脑功能异常，而不是明显的脑结构。本课题中的神经元发生器定位与识别将提供辅助大脑高级功能的神经元活动的来源和时间的补充信息，并形成大脑活动的时空序列图像。这将使来自空间分辨率良好但时间分辨率差的MRI的信息和来自头皮上时间分辨率高的EEG的信息相结合，为临床心理学家和大脑研究人员提供更有效的诊断工具。