電気キャパシタンス・トモグラフィー法による体外循環血流内の血栓検出法の確立

电容断层扫描体外循环血栓检测方法的建立

基本信息

批准号：
22KF0066
负责人：
武居昌宏
金额：
$ 1.47万
依托单位：
Chiba University
依托单位国家：
日本
项目类别：
Grant-in-Aid for JSPS Fellows
财政年份：
2023
资助国家：
日本
起止时间：
2023-03-08 至 2025-03-31
项目状态：
未结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-22KF0066/
关键词：
Lab-on-a-CD electrical measurements Malaria

项目摘要

We are going on with the development of the lab-on-a-CD hardware in Takei laboratory in Nishi Chiba campus of Chiba University. Takei laboratory in Nishi Chiba campus of Chiba University. At the moment, we have managed to assemble the main components of the lab-on-a-CD hardware and improving the stability of the hardware to a robust form that can be easily transported between Takei laboratory in Nishi Chiba campus of Chiba University to the infection and host defense laboratory in Inohana campus of Chiba University where we shall be doing experiments using cultured malaria parasites. Since malaria is not endemic in Japan, the robustness will also enable the lab-on-a-CD hardware to be easily transported to Kenya where we are doing a collaborative research with Jomo Kenyatta University Of Agriculture and Technology (JKUAT) as well the institute of Primate Research (IPR). We are also doing in-vitro sensor analysis using Normal saline at increasing concentration to determine the functionality of each sensor. We are also using a mixture of chicken blood to represent malaria blood mixed with porcine blood to represent normal human blood to check if the hardware can help to determine the volume fraction of chicken blood in the porcine blood. These initial in-vitro studies will help to identify the major problems in the various components of the hardware such as in the 8- sensor array system or the Arduino or any other part that may cause the inconsistences in the impedance measurement results using the novel lab-on-a-CD hardware in diagnosis of malaria.

我们将继续在千叶大学Nishi Chiba校园的Takei实验室中开发实验室CD硬件。千叶大学Nishi Chiba校园的Takei实验室。目前，我们设法组装了实验室-A-CD硬件的主要组成部分，并提高了硬件到可靠形式的稳定性，可以轻松地在Chiba University的Nishi Chiba University的Takei Laboratory之间运输到感染的Nishi Chiba校园之间，并在我们的Inohana University的国防实验室中，在我们的Inohana University中，我们将在其中使用consitectiria carasiria parasiria carasiria carasiria parasiria parasiria parasial carasiaria paras。由于疟疾在日本不是地方性的，因此鲁棒性还将使实验室的A-CD硬件能够轻松地运送到肯尼亚，在那里我们与Jomo Kenyata农业技术大学（JKUAT）进行合作研究，以及灵活研究所（IPR）。我们还使用正常盐水以增加浓度来确定每个传感器的功能。我们还使用鸡血的混合物来代表疟疾血液与猪血混合，以代表正常的人血，以检查硬件是否可以帮助确定猪血中鸡血的体积分数。这些初始的体外研究将有助于确定硬件各个组件中的主要问题，例如8-传感器阵列系统或Arduino或任何其他部分，可能会使用新型的MALARIA诊断实验室-A-CD硬件来引起阻抗测量结果。