Human brain representation of free using fMRI and ECoG

使用 fMRI 和 ECoG 自由表达人脑

• 批准号: 24650226
• 负责人: MIMA Tatsuya
• 金额: $ 2.41万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-24650226/
• 关键词: ニューロエコノミクス; 脳機能イメージング

The present study aims to investigate the effect of free things for human preference by using neuroimaging technique. In addition to the brain map of free, we would like to find out the time course of free processing in human brain using the electrocorticogram recorded in intractable epilepsy patients. For example, it has been reported that the high-grade expensive chocolates and cheep chocolates are simultaneously presented with proper prices, people prefer the former one because it will give them more pleasure. However, if the cheap ones are priced as zero, people prefer to select zero-priced chocolates. By using this experimental paradigm (Shampanier, 2007), we confirmed this inversion of preference behaviorally and our fMRI study revealed the extra-activation of medial prefrontal area for zero-priced things.

本研究旨在利用神经影像技术研究免费事物对人类偏好的影响。除了自由脑图谱外，我们还想利用顽固性癫痫患者记录的皮层电图来了解人脑自由处理的时间过程。例如，据报道，高档昂贵的巧克力和便宜的巧克力同时以适当的价格呈现，人们更喜欢前者，因为它会给他们更多的乐趣。然而，如果便宜的巧克力价格为零，人们更愿意选择零价巧克力。通过使用这种实验范式（Shampanier，2007），我们在行为上证实了这种偏好倒置，并且我们的功能磁共振成像研究揭示了内侧前额叶区域对零价物品的额外激活。

项目成果

Intracortical water diffusion can retain plasticity-induced changes after repetitive transcranial magnetic stimulation through coupling between the stimulated and remote regions

皮质内水扩散可以通过受刺激区域和远程区域之间的耦合来保留重复经颅磁刺激后可塑性引起的变化

• 发表时间: 2014
• 作者: Abe M.;Fukuyama H.;Mima T.
• 通讯作者: Mima T.

Water diffusion reveals networks that modulate multiregional morphological plasticity after repetitive brain stimulation

• DOI: 10.1073/pnas.1320223111
• 发表时间: 2014-03-25
• 期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• 影响因子: 11.1
• 作者: Abe, Mitsunari;Fukuyama, Hidenao;Mima, Tatsuya
• 通讯作者: Mima, Tatsuya