Development of novel nano clothing material for application to health and medical fields

开发应用于健康和医疗领域的新型纳米服装材料

• 批准号: 24650455
• 负责人: TAKASAKI Midori
• 金额: $ 2.41万
• 依托单位: Miyagi University of Education
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-24650455/
• 关键词: エレクトロスピニング

In this study, I carried out to produce polylactide (PLA)nanofibers and textiles having physiological and pharmacological activities using laser electrospinning (LES) method, which is the novel method of solvent-free of a unique technology method.Furthermore,I explored the application of the method as health and medical clothing.As results of investigation of conditions, it was possible to produce the PLA nanofibers containing the drug when laser power was high output, and there was no influence of the thermal degradation of the drug in the LES process.The release of the drug was able to be controlled by varying the fiber diameter. From these results, guidelines for application of the health and medical clothing material was obtained.

本研究利用激光静电纺丝(LES)法制备了具有生理和药理活性的聚乳酸纳米纤维和纺织品，这是一种新型的无溶剂方法，具有独特的工艺方法。此外，我还探索了该方法在保健和医用服装方面的应用。作为条件考察的结果，在激光功率较高的情况下，可以制备含有药物的聚乳酸纳米纤维，并且在LES过程中不受药物热降解的影响。通过改变纤维直径可以控制药物的释放。根据这些结果，得出了保健和医用服装材料的应用指南。

项目成果

Preparation of Ultra-Fine Fiber of Drug-Loaded Poly Lactide by Laser-Heated Electrospinning for Controlled Release of Drug

激光加热静电纺丝制备载药聚丙交酯超细纤维用于药物控释

• 发表时间: 2014
• 作者: Okura T;Mitsuishi Y;Yoon JY;Kitano N;Yoon JE;Himori E;Kim TH;Soma Y;高崎緑
• 通讯作者: 高崎緑

レーザーエレクトロスピニングによる薬剤含有PLA極細繊維の作製と薬剤溶出性

激光静电纺丝含药PLA微纤维的制备及药物洗脱性能

• 发表时间: 2013
• 作者: 布施谷俊太，伊香賀敏文;大越豊;増田正人;前田裕平;井出圭亮，伊香賀敏文，大越豊，増田正人，前田裕平;的場兵和，伊藤章喜，伊香賀敏文，大越豊;高崎緑，星沙代子，吉澤未来，福士夏実，山口裕香，大越豊，平井利博，小村育男
• 通讯作者: 高崎緑，星沙代子，吉澤未来，福士夏実，山口裕香，大越豊，平井利博，小村育男