The initial diagnosis for lung cancer using isotope ratio

为了开发肺癌的检查方法，我们进行了各种测试。结果，所开发的方法可以高精度地测量大量VOC，并且通过少量呼气减轻了患者负担。在呼气试验中，不同食物对呼气的影响几乎没有差异，呼气试验前也没有长时间的禁食和禁饮。吸烟者呼出气含苯量高于非吸烟者。吸烟6h后呼出苯减少。而且，吸薄荷香烟的呼出物包括高水平的苯和甲苯。采用热脱附技术可以对多种挥发性有机物的碳同位素进行高精度、高准确度的测定。

For the development of the inspection method for lung cancer, we conducted various tests. As the results, the developed method can be measured lot of VOCs for high accuracy, and reduced a patient burden by small exhalation. As the exhalation test, there is almost no difference exhalation by different food and no long time by prohibited food and drinks before exhalation test. The exhalation for smokers included benzene than non-smoker. The benzene of exhalation was decreasing after smoking 6 hours. And, the exhalation for smoking menthol cigarettes included high level benzene and toluene. Using thermal desorption system, carbon isotope for many VOCs can be measured for high precision and accuracy.