Development of New Low-molecular-weight Hydrogelators and Their applications to Cell Culture Materials

点击翻译按钮获取中文摘要

In this work (two years), as one of the applications of low-molecular-weight hydrogelators to biomaterials, we studied the application to the cell culture materials. Using our many hydrogelators, the fundamental researches were performed under the different conditions (such as kinds of amino acids, charge of gelators, and concentrations). The L-lysine-based hydrogelators with a negative charge functioned as the most effective cell culture materials when culturing the fibroblast of mouse; especially, L-lysine-based hydrogelators having a sulfonate and a sulfate were very effective. On the other hand, the caltivation of osteoblast on the hydrogels based on the L-lysine hydrogelators was failed.