PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis
PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis
批准号:
24659395
负责人:
SANO Motoaki
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012 至 --
中文摘要
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英文摘要
Urinary excretion of lipocalin-type PGD(2) synthase (L-PGDS), which converts PG H(2) to PGD(2), increases in early diabetic nephropathy. In addition, L-PGDS expression in the tubular epithelium increases in adriamycin-induced nephropathy, suggesting that
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Cooperative Operation of PGD2/FP and 15d-PGJ2/nrf2 Pathway in the L-PGDS-Mediated Cardioprotection.
PGD2/FP 和 15d-PGJ2/nrf2 通路在 L-PGDS 介导的心脏保护中的协同作用。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Yoshinori Katsumata, Motoaki Sano, Tomohiro Matsuhashi, Keiichi Fukuda., Yoshinori Katsumata, Yoshinori Katsumata]
通讯作者:
Yoshinori Katsumata
DOI:
--
发表时间:
2012
期刊:
Circ J.
影响因子:
--
作者:
[Hoshi H, Hao W, Fujita Y, Funayama A, Miyauchi Y, Hashimoto K, Miyamoto K, (他21名), Sano Motoaki]
通讯作者:
Sano Motoaki
Prostaglandin D2-F type prostanoid receptor signaling is a novel cardiomyocyte survival pathway.
前列腺素D2-F型前列腺素受体信号传导是一种新的心肌细胞存活途径。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Yoshinori Katsumata, Motoaki Sano, Tomohiro Matsuhashi, Keiichi Fukuda., Yoshinori Katsumata]
通讯作者:
Yoshinori Katsumata
Lipocalin-type prostaglandin D2 synthase promotes renal interstitial fibrosis via Th2 lymphocyte activation in unilateral ureteral obstruction
脂质运载蛋白型前列腺素 D2 合酶通过 Th2 淋巴细胞活化促进单侧输尿管梗阻肾间质纤维化
DOI:
--
发表时间:
2012
期刊:
J Am Soc Nephrol.
影响因子:
--
作者:
[Ito H, Sano M, Nagata N, Aritake K, Katsumata Y, Xiaoxiang Y, Morizane S, Matsuhashi T, Urade Y, Asano K, Utsunomiya Y, Hosoya T, Fukuda K]
通讯作者:
Fukuda K
DOI:
10.1016/j.jjcc.2012.11.006
发表时间:
2013-03
期刊:
Journal of cardiology
影响因子:
2.5
作者:
[Hiroshi Nakamura;I. Kunitsugu;K. Fukuda;M. Matsuzaki;M. Sano]
通讯作者:
Hiroshi Nakamura;I. Kunitsugu;K. Fukuda;M. Matsuzaki;M. Sano
共 9 条
Elucidation of the molecular mechanism and regulation of T-cell senescence
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批准号:18H02812
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.15万
-
财政年份:2018
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负责人:SANO Motoaki
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依托单位:
Cellular mechanism of cardio-adrenal interaction
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批准号:25670396
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
-
财政年份:2013
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负责人:SANO Motoaki
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依托单位:
A significance of integrated stress response in the heart
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批准号:22659158
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.07万
-
财政年份:2010
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负责人:SANO Motoaki
-
依托单位:
A role of amino acid metabolism in the oxidative stress response
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批准号:20390228
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.15万
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财政年份:2008
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负责人:SANO Motoaki
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依托单位:
Development of novel therapy for heart failure using Cdk9 as a target molecule
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批准号:18390239
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.36万
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财政年份:2006
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负责人:SANO Motoaki
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依托单位:
海外基金