Cell therapy of adipocytes derived from human iPS cells using cellcontainers and animal disease models

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We investigated the function of adipocyte derived from human iPS and ES cells and the survival and maintenance of these cells after transplantation into nude mice. The adipocytes derived from human iPS and ES cells showed adipocyte function such as lipolysis, and survived at least 4 weeks after the transplantation. The adipogenic differentiation and transplantation system in vitro and in vivo is expected to be useful in the study of pathophysiology and to be applied for future cell therapy.