Identification of endometrial cancer stem cell markers
Identification of endometrial cancer stem cell markers
批准号:
24659736
负责人:
KATO Kiyoko
金额:
$2.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2012
资助国家:
日本
项目状态:
已结题
起止时间:
2012-04-01 至 2014-03-31
中文摘要
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英文摘要
We analyzed the association with dbpC/contrin(dbpC) and the character of endometrial cancer stem cells .We designed and constructed a cytomegarovirus vector containing dbpC cDNA, and transfected it into Ishikawa(IK) cells, an endometrial cancer cell line. The expression of ALDH1 was increased in IK-dbpC cells, compared to mock cells,and the ratio of SP cells were more than 10-fold in IK-dbpC cells compared to mock cells . Downreguration of dbpC expression was remarkably reduced the ALDH1 expression and the rate of SP cells, compared to negative control. Microarray analysis showed that one of the cancer/testis antigens was up-regulated in IK-dbpC cells compared with mock cells.
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産婦人科における幹細胞研究
干细胞在妇产科的研究
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Shintaku H, Inaoka T, Nakagawa T, Kawano S, Ito J., 加藤聖子]
通讯作者:
加藤聖子
DOI:
10.1177/0960327111424305
发表时间:
2012-06-01
期刊:
HUMAN & EXPERIMENTAL TOXICOLOGY
影响因子:
2.8
作者:
[Fukushima, K., Tsukimori, K., Wake, N.]
通讯作者:
Wake, N.
子宮内膜、子宮体癌幹細胞の同定と生物学的特性の解析
子宫内膜及子宫内膜癌干细胞生物学特性的鉴定与分析
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Yusuf N, Inagaki T, Kusunoki S, Okabe H, Yamada I, Matsumoto A, Terao T, Takeda S, Kato K, Kiyoko Kato, 加藤聖子, 加藤聖子]
通讯作者:
加藤聖子
DOI:
10.1016/j.ygyno.2013.03.005
发表时间:
2013-06-01
期刊:
GYNECOLOGIC ONCOLOGY
影响因子:
4.7
作者:
[Kusunoki, Soshi, Kato, Kiyoko, Takeda, Satoru]
通讯作者:
Takeda, Satoru
[子宮体癌の生物学的特性から診断、治療まで]癌遺伝子と癌幹細胞
【从生物学特性到子宫内膜癌的诊治】癌基因与癌干细胞
DOI:
--
发表时间:
2012
期刊:
産科と婦人科
影响因子:
--
作者:
[Fukushima K, Tsukimori K, Li D, Takao T, Morokuma S, Kato K, Seki H, Takeda S, Matsumura S, Wake N, Kato K, Kato K, 加藤聖子]
通讯作者:
加藤聖子
共 22 条
Development of new target therapy for endometrial cancer stem cells
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批准号:23390392
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.9万
-
财政年份:2011
-
负责人:KATO Kiyoko
-
依托单位:
Contribution of the genomic diversity to the development and carcinogenesis of endometriosis
-
批准号:22659302
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$1.96万
-
财政年份:2010
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负责人:KATO Kiyoko
-
依托单位:
Analysis of endometrial cancer development
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批准号:17390452
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.71万
-
财政年份:2005
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负责人:KATO Kiyoko
-
依托单位:
Analysis of molecular mechanism in endometrial cancer development.
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批准号:12557138
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.45万
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财政年份:2000
-
负责人:KATO Kiyoko
-
依托单位:
Analysis of signal transaction associated with proliferation and progression in gynecologic cancer
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批准号:11671629
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
-
财政年份:1999
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负责人:KATO Kiyoko
-
依托单位:
Analysis of signal transduction associate with carcinogenesis and progression in endometrial and ovarian carcinoma.
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批准号:08671905
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:1996
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负责人:KATO Kiyoko
-
依托单位:
Role of Ras and Ras-relatd protein for carcinogenesis of endometrial
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批准号:05671379
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
-
财政年份:1993
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负责人:KATO Kiyoko
-
依托单位:
海外基金