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A daring attempt to cure glioblastoma by targeting glucose metabolism as a novel target to control glioma stem cells

A daring attempt to cure glioblastoma by targeting glucose metabolism as a novel target to control glioma stem cells
通过将葡萄糖代谢作为控制胶质瘤干细胞的新靶标来治疗胶质母细胞瘤的大胆尝试
批准号:
25670615
负责人:
KITANAKA Chifumi
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2013
资助国家:
日本
项目状态:
已结题
起止时间:
2013-04-01 至 2014-03-31
关键词:

项目摘要

项目成果

KITANAKA Chifumi的其他基金

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中文摘要
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英文摘要
Increased glucose metabolism often occurs in human cancers, the significance of which for cancer cells remains mostly unclear. In this project, we conducted experiments to test the working hypothesis that glucose metabolism has an essential role in the maintenance of glioma stem cells. The results suggested that inhibition of an intracellular molecule presumed to be involved in glucose metabolism might affect the stemness of glioma stem cells, in support of the idea that glucose metabolism is involved in the maintenance of glioma stem cells.
期刊论文(14)
专著(0)
科研奖励(0)
会议论文
グリオーマ幹細胞
神经胶质瘤干细胞
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Takewa Y, Yamanami M, Kishimoto Y, Arakawa M, Kanda K, Matsui Y, Oie T, Ishibashi-Ueda H, Tajikawa T, Ohba K, Yaku H, Taenaka Y, Tatsumi E, Nakayama Y, 北中千史]
通讯作者: 北中千史
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Kitanaka C, Sato A, Okada M, 北中千史, 北中千史, 佐藤篤,岡田雅司,渋谷慶太,清野静香,成田善孝,渋井壮一郎,北中千史,嘉山孝正, 佐藤篤,岡田雅司,成田善孝,渋井壮一郎,北中千史,嘉山孝正, 岡田雅司,渋谷慶太,佐藤篤,鈴木修平,清野学,北中千史, 北中千史, 北中千史]
通讯作者: 北中千史
A549非小細胞肺癌細胞の腫瘍形成能維持におけるJNKの特異的な役割
JNK在维持A549非小细胞肺癌细胞致瘤潜力中的具体作用
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [Kitanaka C, Sato A, Okada M, 北中千史, 北中千史, 佐藤篤,岡田雅司,渋谷慶太,清野静香,成田善孝,渋井壮一郎,北中千史,嘉山孝正, 佐藤篤,岡田雅司,成田善孝,渋井壮一郎,北中千史,嘉山孝正, 岡田雅司,渋谷慶太,佐藤篤,鈴木修平,清野学,北中千史]
通讯作者: 岡田雅司,渋谷慶太,佐藤篤,鈴木修平,清野学,北中千史
DOI: 10.3892/ijo.2013.2209
发表时间: 2014-02-01
期刊: INTERNATIONAL JOURNAL OF ONCOLOGY
影响因子: 5.2
作者: [Okada, Masashi, Sato, Atsushi, Kitanaka, Chifumi]
通讯作者: Kitanaka, Chifumi
12
    Taking advantage of a pitfall in glioma cancer stem cell epigenetics to develop novel therapies directed to cancer stem cells
    • 批准号:
      16K15640
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.16万
    • 财政年份:
      2016
    • 负责人:
      KITANAKA Chifumi
    • 依托单位:
    An attempt to answer the cardinal question --- why do cancer cells have such a sweet tooth? --- through glioma stem cell research
    • 批准号:
      15K15522
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2015
    • 负责人:
      KITANAKA Chifumi
    • 依托单位:
    An attempt to create an animal model for glioblastoma cure via proving the hypothesis that glucose metabolism serves as a rheostat to determine the cell fate of cancer stem cells
    • 批准号:
      26670635
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2014
    • 负责人:
      KITANAKA Chifumi
    • 依托单位:
    A systematic approach to achieve glioblastoma cure via targeting glioma stem cells
    • 批准号:
      24390338
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.73万
    • 财政年份:
      2012
    • 负责人:
      KITANAKA Chifumi
    • 依托单位: