Development of a new screening method to isolate the genes encoding RNA editing enzyme

在叶绿体和线粒体中，RNA编辑经常发生在大多数陆生植物的许多转录本中。RNA编辑是一种神秘的现象，其中转录本中的特定胞苷(C)被改变为尿苷(U)。自20年前在植物细胞器中发现C-to-U RNA编辑以来，RNA编辑酶或因子仍有待鉴定。在这项研究中，我们利用一种模式植物——小壶菌（Physcomitrella patens）鉴定了几种新的RNA编辑因子。

In chloroplasts and mitochondria, RNA editing frequently occurs in many transcripts of most terrestrial plants. RNA editing is an enigmatic phenomenon in which specific cytidines (C) in the transcripts are changed to uridines (U). Since C-to-U RNA editing was discoveredin plant organelles 20 years ago, the RNA editing enzyme or factors remain to be identified. In this study, we have identified several novel RNA editing factors using a model plant, Physcomitrella patens.