Biological functions of male mice songs平成 25年 4月 25 日現在

在这项研究中，我们证明了1)我们使用双选择测试来确定雌鼠对歌曲的偏好，通过评估对播放歌曲的搜索行为所花费的时间。我们确定雌性老鼠可以区分雄性的歌曲特征，并且雌性天生更喜欢来自不同于其父母的歌曲。(2)这种偏好在交叉抚养中被逆转，在无父亲的抚养条件下消失，表明这种偏好是后天习得的，或者可以通过与父亲的社会经验加以修正。3)雌激素控制了这种偏好。4)雄鸟鸣叫次数与雌鸟成对产仔呈正相关。5)本研究发现，当雌性暴露于肮脏的雄性床上用品或雄性小鼠信息素ESP1时，雌性的偏好被观察到，我们之前报道过这些信息素会增强雌性的性接受性（Nature 2010）。这一结果表明，听觉和嗅觉信号的跨模态信息处理可能影响小鼠的择偶偏好。

In this study, we demonstrated that 1) we used the two-choice test to determine the song preference of female mice by assessing the time engaged in searching behavior towards played-back songs. We determined that female mice can discriminate among male song characteristics and that females innately prefer songs from strains that are different from their parents. 2) this preference was reversed by cross-fostering and disappeared by fatherless rearing conditions, indicating that the preference was learned or could be modified by social experience with their fathers. 3) this preference was controlled under estrogens. 4) there was a positive correlation between emission number of songs of males and giving birth of females in pairs. 5) the preference identified in this study was observed when females were exposed to soiled male bedding or the male mouse pheromone ESP1, which we previously reported enhanced female sexual receptivity (Nature 2010). This result suggests that cross-modal information processing from both acoustic and olfactory signals may influence mate preference in mice.