Elucidation of the tetrodotoxin biosynthesis pathway by whole genome analysis of tetrodotoxin producing bacteria
Elucidation of the tetrodotoxin biosynthesis pathway by whole genome analysis of tetrodotoxin producing bacteria
批准号:
23658173
负责人:
WATABE Shugo
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 --
中文摘要
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英文摘要
The purpose of this study was to elucidate the biosynthesis pathway of pufferfish toxin, tetrodotoxin(TTX), in TTX-producing marine bacterium Vibrio alginolyticus by the whole genome analysis. We identified 6 strains of V. alginolyticus from intestinal flora of pufferfish and TTX was detected from 2 strains by MALDI-TOF-MS analysis. Genomic DNA samples extracted from the TTX-producing V. alginolyticus strains were subjected to whole genome analysis by the next-generation sequencing technology.
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Expression analysis of genes related to tetrodotoxin pharmacokinetics in ovary tissues of wild pufferfish Takifugu rubripes
野生河豚卵巢组织中河豚毒素药代动力学相关基因的表达分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[H. Feroudj, T. Matsumoto, R. Kikuchi, Y. Kawana, H. Kondo, I. Hirono, S. Aki, T. Mochizuki, Y. Nagashima, G. Kaneko, H. Ushio, M. Kodama, S. Watabe]
通讯作者:
S. Watabe
Suppression subtractive hybridization analysis in the skin of cultured marine pufferfish Takifugu snyderi after the intramuscular administration of tetrodotoxin
养殖河豚肌肉注射河豚毒素后皮肤的抑制消减杂交分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[R. Kikuchi, T. Matsumoto, H. Feroudj, H. Doi, T. Ishibashi, Y. Nagashima, G. Kaneko, H. Ushio, M. Kodama, S. Watabe]
通讯作者:
S. Watabe
フグ類皮膚におけるテトロドトキシン関連遺伝子の発現解析とTTX腸内産生菌の単離の試み
河豚鱼皮中河豚毒素相关基因的表达分析及TTX肠道产生菌的分离尝试
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[菊地遼輔, 松本拓也, Feroudj H, 土井啓行, 石橋敏章, 長島裕二, 糸井史朗, 杉田治男, 金子元, 潮秀樹, 児玉正昭, 渡部終五]
通讯作者:
渡部終五
日本水産学会監修,水産学シリーズ第174号「トラフグの生産技術開発と安全確保(仮題)」
日本水产学会监修,水产科学丛书第174号《虎河豚生产技术的开发及确保安全性(暂定名)》
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[T. Yamaguchi, J. Shimajiri, M. Abe, M. Hosokawa and K. Miyashita., 菊地遼輔, 猪原悠太郎・中川聡・澤辺智雄, 松本拓也,渡部終五]
通讯作者:
松本拓也,渡部終五
Microarray analysis of tetrodotoxin accumulation-related genes in the ovary of wild pufferfish Takifugu rubripes
野生河豚卵巢中河豚毒素积累相关基因的微阵列分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Feroudj H, 松本拓也, 菊地遼輔, 川名由利子, 近藤秀裕, 廣野育生, 安藝真一郎, 望月俊孝, 長島裕二, 金子元, 潮秀樹, 児玉正昭, 渡部終五]
通讯作者:
渡部終五
共 7 条
Research on the bivalve osmoregulatory system by transcriptome analysis
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批准号:24658182
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.58万
-
财政年份:2012
-
负责人:WATABE Shugo
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依托单位:
The genome-wide study on the regulation of muscle differentiation in fish
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批准号:19108003
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$66.14万
-
财政年份:2007
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负责人:WATABE Shugo
-
依托单位:
Post-sequencing functional studies on the pufferfish (Takifugu rubripes) genome
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批准号:14104008
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$72.38万
-
财政年份:2002
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负责人:WATABE Shugo
-
依托单位:
Temperature adaptation of fish - molecular mechanisms involved and application
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批准号:11306013
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$25.9万
-
财政年份:1999
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负责人:WATABE Shugo
-
依托单位:
Identification and Utilization of the Region Responsible for Fish Meat Gel Formation with Respect to Improvements of the Quality for Surimi-based Products
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批准号:10356007
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项目类别:Grant-in-Aid for Scientific Research (A).
-
资助金额:$20.1万
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财政年份:1998
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负责人:WATABE Shugo
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依托单位:
Molecular Biological Studies on Functional Properties of Fish Myosin with Reference to Carp Fast Skeletal Muscle
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批准号:07456095
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.03万
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财政年份:1995
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负责人:WATABE Shugo
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依托单位:
Biochemical Studies on Changes in Fish Muscle Proteins Following Temperature Acclimation
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批准号:02454081
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.29万
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财政年份:1990
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负责人:WATABE Shugo
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依托单位:
Studies on Fish Sarcoplasmic Reticulum
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批准号:63560198
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1988
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负责人:WATABE Shugo
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依托单位:
Studies on Changes in Toughness of the Body Wall from Sea Cucumber
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批准号:61560227
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
-
财政年份:1986
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负责人:WATABE Shugo
-
依托单位:
海外基金