Unravelling the mechanism of ovarian carcinogenesis caused by BRCA1 depletion and estrogen action
Unravelling the mechanism of ovarian carcinogenesis caused by BRCA1 depletion and estrogen action
批准号:
26670730
负责人:
OHTA Tomohiko
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-04-01 至 2016-03-31
中文摘要
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英文摘要
期刊论文(21)
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HP1 amma mediates BARD1 retention on Lys9-dimethylated histone H3 at sites of DNA damage
HP1 amma 介导 BARD1 在 DNA 损伤位点保留在 Lys9-二甲基化组蛋白 H3 上
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu]
通讯作者:
Wenwen Wu
ATM-dependent but RNF168-independent BRCA1/BARD1 retention at sites of DNA damage
ATM 依赖性但不依赖 RNF168 BRCA1/BARD1 在 DNA 损伤位点的保留
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Tomohiko Ohta, Hiroyuki Nishikawa, Anna S. Sedukhina, Takayo Fukuda, Wenwen Wu]
通讯作者:
Wenwen Wu
BRCA1の新規クロマチン結合機構を標的としたがん治療戦略
针对 BRCA1 新型染色质结合机制的癌症治疗策略
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Eisaku Kondo, Ken Saito, Hidekazu Iioka, Masakiyo Sakaguchi, 太田智彦]
通讯作者:
太田智彦
DOI:
10.1371/journal.pone.0118002
发表时间:
2015
期刊:
PloS one
影响因子:
3.7
作者:
[Nagasawa S, Sedukhina AS, Nakagawa Y, Maeda I, Kubota M, Ohnuma S, Tsugawa K, Ohta T, Roche-Molina M, Bernal JA, Narváez AJ, Jeyasekharan AD, Sato K]
通讯作者:
Sato K
HERC2 and its interactors in regulation of DNA damage response and cell cycle.
HERC2 及其相互作用因子在 DNA 损伤反应和细胞周期调节中的作用。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[筆宝義隆, 丸喜明, 落合雅子, 松浦哲也, 今井俊夫, 太田智彦]
通讯作者:
太田智彦
共 16 条
A study of mechanism underlying carcinogenesis promoted by estrogen receptor in BRCA1 deficient cells
-
批准号:16K15712
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.16万
-
财政年份:2016
-
负责人:OHTA Tomohiko
-
依托单位:
Functional analysis of BRCA1 as the molecular basis of breast cancer therapy
-
批准号:26290042
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.65万
-
财政年份:2014
-
负责人:OHTA Tomohiko
-
依托单位:
Research on the breast cancer chemotherapy targeting synthetic lethality caused by the factors in the DNA damage repair pathways.
-
批准号:23300358
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$14.06万
-
财政年份:2011
-
负责人:OHTA Tomohiko
-
依托单位:
Analyses of DNA damage response to neoadjuvant chemotherapy in basal-like breast cancer
-
批准号:20591557
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2008
-
负责人:OHTA Tomohiko
-
依托单位:
Study of DNA repair mechanisms that affect chemosensitivity of breast cancer
-
批准号:18591446
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.55万
-
财政年份:2006
-
负责人:OHTA Tomohiko
-
依托单位:
Mechanisms that regulate chromosomal stability through the ubiquitin lipase activity of BRCA1
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批准号:16591280
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2004
-
负责人:OHTA Tomohiko
-
依托单位:
海外基金