How genetic abnormality in keratinocytes, not in melanocytes, causes pigmentary skin disorders?
How genetic abnormality in keratinocytes, not in melanocytes, causes pigmentary skin disorders?
角质形成细胞而非黑素细胞的遗传异常如何导致色素性皮肤病？
批准号：
22K16289
负责人：
ホセイン エムディ・ラジブ
金额：
$3.0万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Early-Career Scientists
财政年份：
2022
资助国家：
日本
项目状态：
未结题
起止时间：
2022-04-01 至 2025-03-31
中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Isolate the K5 mutant (P25L) gene: The K5 mutant gene with the specific mutation (P25L) is obtained by introducing the desired mutation using molecular biology techniques and Cloning the K5 mutant gene into adenovirus victor. generate Crispr-Cas-based knock-in mice with an inducible mutant K5 we have designed guide RNA (gRNA): A specific gRNA is designed to target the desired genomic location where the knock-in will occur.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
海外基金
