Asymmetric catalysis with supported chiral olefin-rhodium complexes in defined porous networks (B03+)

在限定的多孔网络中使用负载的手性烯烃-铑配合物进行不对称催化（B03）

• 批准号: 406662601
• 金额: --
• 依托单位: Institut für Organische Chemie (IOC)
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2018
• 资助国家: 德国
• 起止时间: 2017-12-31 至 2021-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/406662601?language=en
• 关键词: Asymmetric; catalysis; supported; chiral; olefin

The aim is to understand and control chirality transfer, catalytic activity and mechanism of chiral diene-metal complexes covalently tethered inside a mesoporous material by using the asymmetric Rh-catalyzed 1,4-addition of boronic acids to enones as a benchmark system. The confinement effects resulting from a) the steric confinement of the catalyst and substrate in a pore of certain size and geometry, b) the polarity gradient between the inner pore surface and the catalyst in the centre and c) solvent interactions with inner pore surface and the ligand sphere will be examined by various experimental and theoretical methods.

目的是了解和控制手性二烯-金属配合物共价连接在介孔材料内的手性转移，催化活性和机制，通过使用不对称铑催化的硼酸对烯酮的1，4-加成反应作为基准系统。将通过各种实验和理论方法来检查由a）催化剂和基底在一定尺寸和几何形状的孔中的空间限制，B）内孔表面和中心的催化剂之间的极性梯度和c）溶剂与内孔表面和配体球的相互作用产生的限制效应。