DEVELOPMENT OF COMPUTER CONTROLLED CARDIO-PULMONARY BYPASS SYSTEM

计算机控制心肺转流系统的研制

• 批准号: 62870054
• 负责人: IMAI Yasuharu
• 金额: $ 3.07万
• 依托单位: TOKYO WOMEN'S MEDICAL COLLEGE
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-62870054/
• 关键词: Computer control; Automatic control; Cardio-Pulmonary bypass; Extracorporeal circulation; Pulsatile flow; Roller pump; コンピュータコントロール

A pulsatile roller pump and an automatic flow control system for cardio-pulmonary bypass (CPB) have been developed. The pulsatile pump has a newly designed head casing to reduce relative fluctuation of flow and pressure waveform. The clearance between rollers and the casing varies such that the volume of pumping tube is directly proportional to the angle of rotor rotation. In vitro experiments shows that the relative fluctuation ratio is ranging from 30 to 85 % of conventional roller dump. In clinical cases, the pump produced pulsatile pressure waveform satisfactory. The reliability of the pump was probed by 200 clinical cases.The automatic control system consists of pumps and 16 bit micro-computer. The micro-computer completely controls blood flow and pressure throughout CPB. the digital PI (Proportional-Integral) control algorithm with a sampling period of 1 second, is used for flow controller. The results of 20 dog experiments indicate that this control system maintains infusion and withdrawal flow satisfactory.

研制了一种脉动滚子泵和一种用于心肺旁路（CPB）的自动流量控制系统。为了减小脉动泵的流量和压力波形的相对波动，新设计了泵头套管。由于转子与机匣之间的间隙不同，泵管的体积与转子旋转角度成正比。体外试验表明，相对波动率为常规滚筒式排土场的30% ~ 85%。在临床上，该泵产生了令人满意的脉动压力波形。通过200例临床病例对泵的可靠性进行了探讨。自动控制系统由泵和16位微机组成。微电脑完全控制整个CPB的血流和血压。流量控制器采用采样周期为1秒的数字PI（比例积分）控制算法。20只狗的实验结果表明，该控制系统能保持良好的输注和退出流量。

项目成果

Beppu T.; Imai Y.; Kurosawa H.; Soejima K.; Suzuki S.; Tsuchiya K.; Fukui Y.: "Pulsatile Roller Pump for Infant's Cardio-Pulmonary Bypass" Jpn J. Artif. Organs. 17. 1396-1399 (1988)

别府T.；

別府俊幸、福井康裕: 医用電子と生体工学. 25. 198-204 (1987)

Toshiyuki Beppu，Yasuhiro Fukui：医疗电子学和生物工程 25. 198-204 (1987)。

Soejima K.; Nakae S.; Kurosawa H.; Imai Y.; Koyanagi H.; Suzuki S.; Kazama S.; Sasaki A.: "Alokalosis and Blood Mass Formation" Jpn J. Artif. Organs. 17. 1417-1421 (1988)

副岛K.；

副島健市、今井康晴、別府俊幸、福井康裕、土屋喜一: 人工臓器掲載予定.

Kenichi Soejima、Yasuharu Imai、Toshiyuki Beppu、Yasuhiro Fukui、Kiichi Tsuchiya：人造器官的计划出版。

副島健市、今井康晴、別府俊幸、福井康裕、土屋喜一: 人工臓器.

副岛健一、今井泰晴、别府俊之、福井康宏、土屋喜一：人工器官。