Development of comuter controlled assisted circulation system

微机控制辅助循环系统的研制

• 批准号: 05671137
• 负责人: IMAI Yasuharu
• 金额: $ 1.28万
• 依托单位: Tokyo Women's Medical College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-05671137/
• 关键词: cardiopulmonary bypass; assisted circulation; centrifugal pump; computer control; microcomputer; automatic control

A pump control system for a cardiopulmonary bypass is developed utilizing a microcomputer. The parameters monitored by the computer are central venous pressure, aortic pressure, blood volume in a reservoir, and collapsing of a small vinyl bag in a venous withdrawal tube. Both pumps in the arterial infusion and the venous withdrawal line are automatically controlled through an interface unit throughout cardiopulmonary bypass. The system regulates central venous pressure with a proportional-integral control algorithm to maintain intravascular volume constant. A screening algorithm is devised to remove artifacts introduced to the pressure measurement. At the weaning period, a perfusionist can select either the central venous pressure control, or a reservoir blood volume control. Computerized pump-purfusion was applied on 100 children cases during open heart surgery, where perfusion flow and central venous pressure were controlled satisfactorily with stable operation. Compared with conventional manually controlled pump-perfusion, no significant difference was noted in mean aortic pressure and central venous pressure, net fluid balance, total urination, blood chemistry, and urinalysis. This system is useful and is expected to improve the safety of pump-perfusion.

本文介绍了一种利用微机实现的体外循环泵控制系统。由计算机监测的参数是中心静脉压、主动脉压、储血器中的血容量和静脉抽取管中的小乙烯袋的塌陷。在整个心肺转流过程中，动脉输注和静脉回输管路中的两个泵均通过接口单元自动控制。该系统通过比例积分控制算法调节中心静脉压，以保持血管内容量恒定。设计了一种筛选算法来去除引入压力测量的伪影。在脱机期，灌注师可以选择中心静脉压控制或储血器血容量控制。本文对100例小儿心内直视手术中应用电脑泵灌注，灌注流量和中心静脉压控制满意，手术稳定。与传统的手动控制泵灌注相比，平均主动脉压和中心静脉压，净液体平衡，总排尿，血液化学和尿液分析没有显着差异。该系统是有用的，并有望提高泵灌注的安全性。

项目成果

T.Beppu,Y.Imai,Y.Fukui: "A computerized control system for cardiopulmonary bypass." J Thorac Cardiovasc Surg. (in press).

T.Beppu，Y.Imai，Y.Fukui：“体外循环的计算机控制系统。”

T. Beppu, Y. Imai, Y. Fukui: "A computerized control system for cardiopulmonary bypass" J Thorac Cardiovasc Surg. (in press).

T. Beppu、Y. Imai、Y. Fukui：“体外循环的计算机控制系统” J Thorac Cardiovasc Surg。

Toshiyuki Beppu, Yasuharu Imai, Yasuhiro Fukui: "A computerized control system for cardiopulmonary bypass." J Thorac Cardiovasc Surg. (in press).

Toshiyuki Beppu、Yasuharu Imai、Yasuhiro Fukui：“体外循环的计算机控制系统。”