Interfaces and Interventions in Complex Chronic Conditions

最近医学的进步提高了人们的生活质量和预期寿命。尽管取得了这一成功，但仍存在一些挑战，包括将生物学知识和疾病发病机制转化为临床护理和复杂慢性疾病患者的护理。两年前，曼海姆医学院决定建立一个专门针对转化医学的临床医生科学家计划，并扩展该学院在转化研究方面的现有教育和培训计划。目前的转化医师科学家（TraPS）项目包括一个单独的研究项目，包括临床试验项目（Track a）或基础或转化研究项目（Track B）。此外，教育和培训计划提供临床试验设计和实施的基础知识，以及转化研究的基本概念和工具。通过DFG目前的项目，我们打算进一步发展我们的转化项目，成为一个新的临床医生科学家项目，解决复杂慢性疾病患者的科学、研究和临床护理方面的具体挑战。复杂的慢性疾病构成了一个严重和日益严重的保健问题，因为目前在科学、研究和医学方面以单一疾病为基础的传统方法阻碍了对这一日益增加的患者群体进行全面了解和跨学科护理的新概念的发展。因此，新的IICCC计划还将包括上述的一个研究项目，然而，该项目也将解决复杂慢性疾病的具体挑战，包括它们的接口和对这一患者群体的新干预措施。此外，现有课程将包括其他教育和培训项目，如数字卫生、数据整合和这些疾病的临床护理。在新的IICCC方案内，临床科学家也将加入现有的研究联盟，并参加这些联盟的特别培训方案。关于这个为期3年的临床培训计划，临床科学家将被要求在其他部门和学科中进行强制性的临床轮转，这些部门和学科与他们自己的学科有接口，以进一步促进跨学科的护理和对这些疾病的理解。每位候选人将获得2名导师的支持，并定期进行评估。通过我们的新项目，我们的目标是为复杂慢性疾病的转化医学学术生涯提供可持续的基础，这也将导致对不断增长的患者群体的改善护理。为高级临床科学家提供支持的进一步计划将得到发展。

Recent progress in medicine has led to improved quality of life and life expectancy. Despite this success several challenges remain, including the translation of knowledge in biology and pathogenesis of disease into clinical care and the care of patients with complex chronic conditions. Two years ago the Medical Faculty Mannheim decided to establish a Clinician Scientist Programme that specifically addresses translational medicine and extends the existing educational and training programmes in the translational research track of the Faculty. The present Translational Physician Scientist (TraPS) Programme includes an individual research project with either a clinical trial project (Track A) or a basic or translational research project (Track B). In addition, an educational and training programme provides basics in clinical trial design and conduct, as well as in the basic concepts and tools of translational research. With the present programme of the DFG we intend to further develop our translational programme to a new Clinician Scientist programme that addresses the specific challenges of science, research and clinical care of patients with complex chronic conditions. Complex chronic conditions present a serious and increasing health care problem, inasmuch as the present traditional single-disease based approach in science, research and medicine hampers the development of new concepts for comprehensive understanding and interdisciplinary care of this increasing patient population. Therefore, the new IICCC programme will also include a research project as outlined above, which, however, will also address the specific challenges of complex chronic conditions, including their interfaces and new interventions in this patient population. In addition, the existing curriculum will contain additional lines of education and training, such as digital health, data integration and the clinical care of these diseases. Within the new IICCC programme the Clinician Scientists will also be affiliated with the existing research consortia and will attend the special training programmes of these consortia. With regard to the clinical training in this 3 year programme, Clinician Scientists will be required to perform mandatory clinical rotations into other departments and disciplines which have interfaces with their own discipline, in order to further foster interdisciplinary care and understanding of these conditions. Each candidate will be supported by 2 mentors and the programme will undergo regular evaluation. With our new programme we aim to provide a sustainable basis for an academic career in translational medicine of complex chronic conditions, which will also lead to improved care of this ever growing patient population. Further programmes to provide support for Advanced Clinician Scientists will be developed.