Interfaces and Interventions in Complex Chronic Conditions

最近的医学进步提高了人们的生活质量和预期寿命。尽管取得了这一成功，但仍然存在一些挑战，包括将生物学和疾病发病机制方面的知识转化为临床护理和复杂慢性病患者的护理。两年前，曼海姆医学院决定建立一个专门针对转化医学的临床医生科学家方案，并将现有的教育和培训方案扩展到该学院的转化性研究领域。目前的转化医学科学家计划(TRIPS)包括个人研究项目，包括临床试验项目(Track A)或基础或转译研究项目(Track B)。此外，教育和培训方案提供临床试验设计和实施的基础知识，以及转化性研究的基本概念和工具。通过DFG目前的计划，我们打算将我们的翻译计划进一步发展为一个新的临床医生科学家计划，以解决复杂慢性病患者在科学、研究和临床护理方面的具体挑战。复杂的慢性疾病是一个严重且日益严重的卫生保健问题，因为目前科学、研究和医学中传统的以单一疾病为基础的方法阻碍了全面了解和跨学科护理这一日益增长的患者群体的新概念的发展。因此，新的IICCC方案还将包括如上所述的一个研究项目，但该项目也将解决复杂慢性疾病的具体挑战，包括它们之间的相互作用和在这一患者群体中的新干预措施。此外，现有课程将包含额外的教育和培训，如数字健康、数据整合和这些疾病的临床护理。在新的IICCC方案中，临床医生科学家也将隶属于现有的研究联盟，并将参加这些联盟的特别培训方案。在这三年计划中的临床培训方面，临床医生科学家将被要求进行强制临床轮换到其他与他们自己的学科接轨的部门和学科，以进一步促进跨学科护理和对这些情况的了解。每名候选人将得到两名导师的支持，该方案将接受定期评估。通过我们的新计划，我们的目标是为复杂慢性病转化医学的学术生涯提供一个可持续的基础，这也将导致对不断增长的患者群体的更好的护理。将制定进一步的方案，为高级临床医生科学家提供支持。

Recent progress in medicine has led to improved quality of life and life expectancy. Despite this success several challenges remain, including the translation of knowledge in biology and pathogenesis of disease into clinical care and the care of patients with complex chronic conditions. Two years ago the Medical Faculty Mannheim decided to establish a Clinician Scientist Programme that specifically addresses translational medicine and extends the existing educational and training programmes in the translational research track of the Faculty. The present Translational Physician Scientist (TraPS) Programme includes an individual research project with either a clinical trial project (Track A) or a basic or translational research project (Track B). In addition, an educational and training programme provides basics in clinical trial design and conduct, as well as in the basic concepts and tools of translational research. With the present programme of the DFG we intend to further develop our translational programme to a new Clinician Scientist programme that addresses the specific challenges of science, research and clinical care of patients with complex chronic conditions. Complex chronic conditions present a serious and increasing health care problem, inasmuch as the present traditional single-disease based approach in science, research and medicine hampers the development of new concepts for comprehensive understanding and interdisciplinary care of this increasing patient population. Therefore, the new IICCC programme will also include a research project as outlined above, which, however, will also address the specific challenges of complex chronic conditions, including their interfaces and new interventions in this patient population. In addition, the existing curriculum will contain additional lines of education and training, such as digital health, data integration and the clinical care of these diseases. Within the new IICCC programme the Clinician Scientists will also be affiliated with the existing research consortia and will attend the special training programmes of these consortia. With regard to the clinical training in this 3 year programme, Clinician Scientists will be required to perform mandatory clinical rotations into other departments and disciplines which have interfaces with their own discipline, in order to further foster interdisciplinary care and understanding of these conditions. Each candidate will be supported by 2 mentors and the programme will undergo regular evaluation. With our new programme we aim to provide a sustainable basis for an academic career in translational medicine of complex chronic conditions, which will also lead to improved care of this ever growing patient population. Further programmes to provide support for Advanced Clinician Scientists will be developed.